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Pcdhga12 Gene Detail
Summary
  • Symbol
    Pcdhga12
  • Name
    protocadherin gamma subfamily A, 12
  • Synonyms
    pc2c, Pcdh13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1935229
    NCBI Gene: 93724
  • Member of
    Pcdhg cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37898633-37974926 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.63 cM, cytoband C
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2057 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1935229
 protein coding gene Chr18:37898633-37974926 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024350
 protein coding gene Chr18:36173156-36259977 (+)
A/J MGP_AJ_G0024317
 protein coding gene Chr18:34934357-35011794 (+)
AKR/J MGP_AKRJ_G0024286
 protein coding gene Chr18:35892351-35972570 (+)
BALB/cJ MGP_BALBcJ_G0024317
 protein coding gene Chr18:35000318-35077409 (+)
C3H/HeJ MGP_C3HHeJ_G0024083
 protein coding gene Chr18:35961160-36038769 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024759
 protein coding gene Chr18:37473111-37559702 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022198
 protein coding gene Chr18:34951408-35028291 (+)
CAST/EiJ MGP_CASTEiJ_G0023558
 protein coding gene Chr18:35896091-35977834 (+)
CBA/J MGP_CBAJ_G0024053
 protein coding gene Chr18:38583608-38667943 (+)
DBA/2J MGP_DBA2J_G0024183
 protein coding gene Chr18:34534525-34611340 (+)
FVB/NJ MGP_FVBNJ_G0024149
 protein coding gene Chr18:34243771-34321591 (+)
LP/J MGP_LPJ_G0024267
 protein coding gene Chr18:36243325-36321813 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024180
 protein coding gene Chr18:39846841-39929365 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024808
 protein coding gene Chr18:35745619-35837204 (+)
PWK/PhJ MGP_PWKPhJ_G0023302
 protein coding gene Chr18:34738454-34819114 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023107
 protein coding gene Chr18:35973956-36054330 (+)
WSB/EiJ MGP_WSBEiJ_G0023621
 protein coding gene Chr18:35650640-35737854 (+)



Homology
more
  • Human Ortholog
    PCDHGA12, protocadherin gamma subfamily A, 12
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHGA12, protocadherin gamma subfamily A, 12
  • Synonyms
    CDH21, FIB3, PCDH-GAMMA-A12
  • Links
    NCBI Gene ID: 26025
    UniProt: O60330

  • Chr Location
    5q31.3; chr5:141430507-141512975 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    908
  • Tissues
    67
  • cDNA Data
    11
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93724 NCBI Gene Model | MGI Sequence Detail 76294 C57BL/6J ±  kb
transcript NM_033595 RefSeq | MGI Sequence Detail 5080 C57BL/6  
polypeptide NP_291073 RefSeq | MGI Sequence Detail 932 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR020894 Cadherin conserved site
    IPR031904 Cadherin, C-terminal catenin-binding domain
    IPR032455 Cadherin, cytoplasmic C-terminal domain
    IPR002126 Cadherin-like
    IPR015919 Cadherin-like superfamily
    IPR013164 Cadherin, N-terminal
    IPR050174 Protocadherin/Cadherin-related Cell Adhesion
  • GlyGen
    Q91XY7 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 19
    Genomic 2
    cDNA 12
    Primer pair 3
    Other 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:1353490
References
more
  • Summaries
    All 30
    Developmental Gene Expression 9
    Phenotypes 4
  • Earliest
    J:60527 Hirano S, et al., Protocadherin 2C: a new member of the protocadherin 2 subfamily expressed in a redundant manner with OL-protocadherin in the developing brain. Biochem Biophys Res Commun. 1999 Jul 14;260(3):641-5
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/09/2026
MGI 6.24 		The Jackson Laboratory