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Tlcd2 Gene Detail
Summary
  • Symbol
    Tlcd2
  • Name
    TLC domain containing 2
  • Synonyms
    2010305C02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917141
    NCBI Gene: 380712
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
  • Regulated by
    Rr367 (1 regulatory region)
Location &
Maps
more
  • Sequence Map
    Chr11:75358771-75361725 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 45.91 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917141
 protein coding gene Chr11:75352541-75361725 (+)
129S1/SvImJ ENSMUSG00200045598
 protein coding gene Chr11:72475458-72478369 (+)
A/J ENSMUSG00195038314
 protein coding gene Chr11:72346728-72349699 (+)
AKR/J ENSMUSG00220041657
 protein coding gene Chr11:72569038-72572006 (+)
BALB/cJ ENSMUSG00180034155
 protein coding gene Chr11:72542295-72545260 (+)
C3H/HeJ ENSMUSG00175037331
 protein coding gene Chr11:72512200-72515166 (+)
C57BL/6NJ ENSMUSG00215032954
 protein coding gene Chr11:72135186-72138161 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016739
 protein coding gene Chr11:70387104-70398379 (+)
CAST/EiJ ENSTCUG00005053603
 protein coding gene Chr11:72037801-72040212 (+)
CBA/J ENSMUSG00210046008
 protein coding gene Chr11:72330676-72333646 (+)
DBA/2J ENSMUSG00185039558
 protein coding gene Chr11:72600672-72603638 (+)
FVB/NJ ENSMUSG00205029213
 protein coding gene Chr11:72438377-72441354 (+)
JF1/MsJ ENSUMUG00000042240
 protein coding gene Chr11:72985594-72988062 (+)
LP/J ENSMUSG00230041663
 protein coding gene Chr11:73631311-73634277 (+)
NOD/ShiLtJ ENSMUSG00190044870
 protein coding gene Chr11:72647087-72650053 (+)
NZO/HlLtJ ENSMUSG00225037659
 protein coding gene Chr11:75804729-75807704 (+)
PWK/PhJ ENSLUMG00010020203
 protein coding gene Chr11:72502854-72505323 (+)
SPRET/EiJ ENSMSPG00010041670
 protein coding gene Chr11:72903256-72905979 (+)
WSB/EiJ ENSIUOG00005033059
 protein coding gene Chr11:72501038-72503990 (+)



Homology
more
  • Human Ortholog
    TLCD2, TLC domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TLCD2, TLC domain containing 2
  • Links
    NCBI Gene ID: 727910
    UniProt: A6NGC4

  • Chr Location
    17p13.3; chr17:1702816-1710377 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    608
  • Tissues
    8
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380712 NCBI Gene Model | MGI Sequence Detail 2955 C57BL/6J ±  kb
transcript NM_027249 RefSeq | MGI Sequence Detail 1424 C57BL/6  
polypeptide Q8VC26 UniProt | EBI | MGI Sequence Detail 310 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory