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Scd3 Gene Detail
Summary
  • Symbol
    Scd3
  • Name
    stearoyl-coenzyme A desaturase 3
  • Synonyms
    4930513N16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353437
    NCBI Gene: 30049
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:44191727-44232455 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 37.98 cM, cytoband D2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    991 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353437
 protein coding gene Chr19:44191708-44232455 (+)
129S1/SvImJ ENSMUSG00200020833
 protein coding gene Chr19:40909685-40943981 (+)
A/J ENSMUSG00195014280
 protein coding gene Chr19:41030946-41075491 (+)
AKR/J ENSMUSG00220018590
 protein coding gene Chr19:40829335-40870130 (+)
BALB/cJ ENSMUSG00180020391
 protein coding gene Chr19:41283342-41327883 (+)
C3H/HeJ ENSMUSG00175006337
 protein coding gene Chr19:40818376-40859155 (+)
C57BL/6NJ ENSMUSG00215004692
 protein coding gene Chr19:40881936-40922724 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022995
 protein coding gene Chr19:40873040-40909883 (+)
CAST/EiJ ENSTCUG00005016714
 protein coding gene Chr19:40469279-40505946 (+)
CBA/J ENSMUSG00210018759
 protein coding gene Chr19:40898052-40938840 (+)
DBA/2J ENSMUSG00185008051
 protein coding gene Chr19:41407016-41451561 (+)
FVB/NJ ENSMUSG00205016943
 protein coding gene Chr19:40333180-40367486 (+)
JF1/MsJ ENSUMUG00000035178
 protein coding gene Chr19:41557029-41593943 (+)
LP/J ENSMUSG00230018850
 protein coding gene Chr19:42179613-42213918 (+)
NOD/ShiLtJ ENSMUSG00190004868
 protein coding gene Chr19:40756874-40801333 (+)
NZO/HlLtJ ENSMUSG00225041577
 protein coding gene Chr19:45766022-45806820 (+)
PWK/PhJ ENSLUMG00010000892
 protein coding gene Chr19:40727361-40760412 (+)
SPRET/EiJ ENSMSPG00010007472
 protein coding gene Chr19:40475602-40510381 (+)
WSB/EiJ ENSIUOG00005005916
 protein coding gene Chr19:40275364-40316178 (+)



Homology
more
  • Human Ortholog
    SCD, stearoyl-CoA desaturase
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCD, stearoyl-CoA desaturase
  • Synonyms
    FADS5, hSCD1, MSTP008, SCD1, SCDOS
  • Links
    NCBI Gene ID: 6319
    UniProt: O00767

  • Chr Location
    10q24.31; chr10:100346508-100364837 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1076
  • Tissues
    155
  • cDNA Data
    23
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 30049 NCBI Gene Model | MGI Sequence Detail 40729 C57BL/6J ±  kb
transcript NM_024450 RefSeq | MGI Sequence Detail 3470 Not Specified  
polypeptide Q99PL7 UniProt | EBI | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 23
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1922315
References
more
  • Summaries
    All 43
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:59876 Parimoo S, et al., Identification of a novel SCD gene and expression of the SCD gene family in mouse skin. J Investig Dermatol Symp Proc. 1999 Dec;4(3):320-2
  • Latest
    J:363142 Peters F, et al., Sphingolipid metabolism orchestrates establishment of the hair follicle stem cell compartment. J Cell Biol. 2025 Apr 7;224(4)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory