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MGI News
May 30, 2016
LacZ knock in reporter data for 644 targeted mutants have been imported into GXD from the International Mouse Phenotyping Consortium (IMPC). This set includes 20,139 images and their 21,694 annotated results, obtained from embryonic day 12.5 and postnatal adult specimens. These data are fully integrated into GXD, allowing them to be searched in context of all other gene expression data in GXD. The entire set can be viewed at J:228563.
March 21, 2016
The MGI 6.03 release provides improvements to SNPs searches and batch Gene Expression data.
SNP Query enhancements:
  • The new MGI Mouse dbSNP Query is easier to use, provides vastly improved performance and updated data (dbSNP Build 142).
  • You can filter your results by dbSNP Function Classes and drag columns to reposition strains of interest.
Gene Expression Batch Search:
  • A Batch Search utility has been added, as a third tab, to the Gene Expression Data Query to facilitate searches for expression data using lists of gene symbols or IDs. You can search by either uploading a list of symbols or IDs from tab-delimited or comma-separated files or by copying and pasting a list into the text search box.
  • In addition, the genes field of the Standard Search now accepts comma-separated lists of gene symbols.
  • All Gene Expression Data searches return a tissue-by-gene matrix view as part of its multi-tabbed data summary; this view enables a comparison of expression patterns between genes. Data filters found on the summary pages can be used to further refine search results.
Links to Wikipedia human gene pages:
  • MGI Gene Detail pages now provide links to Wikipedia pages for human gene information. The MyGene.info project organizes these Wikipedia pages and MGI links to these pages only for genes that have a one-to-one mouse/human orthology relationship.
January 14, 2016
The MGI 6.02 release provides improvements to recombinase searches and Gene Ontology (GO) data.
Recombinase enhancements:
  • The MGI Recombinase search now permits querying for anatomical structures AND a driver.
  • The Driver field is now an autocomplete field.
  • Your recombinase search results can now be filtered by Driver, Inducer, Detected and Not Detected (anatomical system) columns.
  • In your search summary, if an inducer is required to activate recombinase activity, then the inducer is now indicated in the summary.
A tutorial for finding recombinase alleles in MGI is available at YouTube.
GO data enhancements:
  • GO tables contain a new Category column. Categories are from a subset of the Gene Ontologies (a "GO slim") and each category provides an overview of a section of the ontology.
  • A new Context column adds value to the GO classification term by detailing the conditions or refining the tissue used in the experiment.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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