Erdr1x MGI Mouse Gene Detail - MGI:2384747 - erythroid differentiation regulator 1 x

Erdr1x Gene Detail

Symbol

Erdr1x
Name

erythroid differentiation regulator 1 x
Synonyms

edr, Erdr1, Gm21887, MGC:5764

Feature Type

protein coding gene

BioType Conflict
IDs

MGI:2384747
NCBI Gene: 170942
Alliance

gene page
Transcription Start Sites

15 TSS
Homologous PAR Feature

Erdr1y

Sequence Map

ChrX:168792655-168802277 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome XY, Syntenic
Mapping Data

2 experiments

Strain Annotations

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2384747	protein coding gene	ChrX:168792655-168802277 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

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Gene Tree

Erdr1x

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Phenotype Summary

6 phenotype references

All Mutations and Alleles

7
Gene trapped

7
Find Mice (IMSR)

7 strains or lines available

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All GO Annotations

3
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

97
Tissues

37
cDNA Data

33
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

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Erdr1x interacts with 22 markers (Mir218-1, Mir218-2, Mir293, ...) View All

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All Sequences

13
UniProt

2

Ensembl

ENSMUSG00000095562 (Evidence)
NCBI Gene

170942 (also overlaps Erdr1y)

			Length	Strain/Species	Flank
genomic	ENSMUSG00000095562	Ensembl Gene Model \| MGI Sequence Detail	9623	C57BL/6J	± kb
transcript	ENSMUST00000238482	Ensembl \| MGI Sequence Detail	1163	Not Applicable
polypeptide	O88727	UniProt \| EBI \| MGI Sequence Detail	177	Not Applicable

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UniProt

2 Sequences

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All nucleic 36

cDNA 34

Primer pair 1

Other 1

Microarray probesets 2

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MGI:5434051, MGI:6847656

Summaries

All 28

Developmental Gene Expression 3

Gene Ontology 2

Phenotypes 6
Earliest

J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
Latest

J:182194 Jung MK, et al., Erythroid differentiation regulator 1, an interleukin 18-regulated gene, acts as a metastasis suppressor in melanoma. J Invest Dermatol. 2011 Oct;131(10):2096-104

TSS for Erdr1x:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr162766	ChrX:168791337-168791359 (+)	-1,307 bp
Tssr5722	ChrX:168792261-168792272 (+)	-388 bp
Tssr5723	ChrX:168792285-168792287 (+)	-369 bp
Tssr5724	ChrX:168792604-168792618 (+)	-44 bp
Tssr5725	ChrX:168792641-168792667 (+)	-1 bp
Tssr5726	ChrX:168792678-168792706 (+)	37 bp
Tssr5727	ChrX:168792718-168792733 (+)	71 bp
Tssr5728	ChrX:168792794-168792814 (+)	149 bp
Tssr5729	ChrX:168793117-168793172 (+)	490 bp
Tssr5730	ChrX:168793339-168793347 (+)	688 bp
Tssr5731	ChrX:168794426-168794438 (+)	1,777 bp
Tssr5732	ChrX:168800147-168800183 (+)	7,510 bp
Tssr5733	ChrX:168800425-168800432 (+)	7,774 bp
Tssr5734	ChrX:168801110-168801119 (+)	8,460 bp
Tssr5735	ChrX:168801248-168801255 (+)	8,597 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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