Hspa1b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hspa1b
heat shock protein 1B
MGI:99517

11 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hspa1b^tm1.1Msk/Hspa1b^tm1.1Msk involves: 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal cell physiology	J:72943
Hspa1b^tm1Bwy/Hspa1b^tm1Bwy B6.129P2-Hspa1b^tm1Bwy	increased cerebral infarct size	J:103999
Hspa1b^tm1Bwy/Hspa1b^tm1Bwy B6.129P2-Hspa1b^tm1Bwy	increased susceptibility to ischemic brain injury	J:103999
Hspa1b^tm1Clib/Hspa1b^tm1Clib involves: 129P2/OlaHsd * C57BL/6	abnormal response/metabolism to endogenous compounds	J:123913
	decreased body temperature	J:123913
	increased susceptibility to induced morbidity/mortality	J:123913
Hspa1b^tm1Clib/Hspa1b^tm1Clib involves: 129P2/OlaHsd * C57BL/6J	abnormal nitric oxide homeostasis	J:76801
	abnormal response/metabolism to endogenous compounds	J:76801
	decreased body temperature	J:76801
	increased interleukin-6 secretion	J:76801
	increased susceptibility to induced morbidity/mortality	J:76801
Hspa1b^tm1Jss/Hspa1b^tm1Jss involves: C57BL/6	increased cellular sensitivity to oxidative stress	J:97232
Hspa1b^tm1Jss/Hspa1b^tm1Jss involves: C57BL/6	increased kidney apoptosis	J:97232
Hspa1b^tm1Msk/Hspa1b⁺ involves: 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal cell physiology	J:72943
Hspa1b^tm1Msk/Hspa1b^tm1Msk involves: 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal cell physiology	J:72943
	increased sensitivity to induced cell death	J:72943

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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