Hspa1b^tm1Jss
Targeted Allele Detail

Summary

• Symbol: Hspa1b^tm1Jss
• Name: heat shock protein 1B; targeted mutation 1, Jeong-Sun Seo
• MGI ID: MGI:3575001
• Synonyms: hsp70.1^-
• Gene: Hspa1b Location: Chr17:35175412-35178214 bp, - strand Genetic Position: Chr17, 18.5 cM
• Alliance: Hspa1b^tm1Jss page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97232
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced the promoter and part of the coding sequence. Northern blot of mutant MEFs confirmed the absence of transcript. (J:97232)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hspa1b Mutation: 23 strains or lines available

References

• Original: J:97232 Shim EH, et al., Targeted disruption of hsp70.1 sensitizes to osmotic stress. EMBO Rep. 2002 Sep;3(9):857-61
• All: 7 reference(s)