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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Adora2b
adenosine A2b receptor
MGI:99403
34 phenotypes from 6 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Adora2btm1.1(KOMP)Vlcg/Adora2b+
B6N(Cg)-Adora2btm1.1(KOMP)Vlcg/J
convulsive seizures J:211773
increased circulating HDL cholesterol level J:211773
increased fasted circulating glucose level J:211773
Adora2btm1.1(KOMP)Vlcg/Adora2btm1.1(KOMP)Vlcg
B6N(Cg)-Adora2btm1.1(KOMP)Vlcg/J
increased circulating alkaline phosphatase level J:211773
Adora2btm1.1Msit/Adora2btm1.1Msit
either: (involves: C57BL/6) or (involves: C57BL/6 * CD-1 * ICR)
abnormal macrophage physiology J:169155
decreased sensitivity to induced morbidity/mortality J:169155
decreased susceptibility to injury J:169155
increased heart rate J:169155
increased interleukin-6 secretion J:169155
increased mean systemic arterial blood pressure J:169155
increased systemic arterial systolic blood pressure J:169155
increased tumor necrosis factor secretion J:169155
Adora2btm1.1Msit/Adora2btm1.1Msit
involves: BALB/cJ
increased susceptibility to injury J:203572
Adora2btm1Dgen/Adora2btm1Dgen
B6.129P2-Adora2btm1Dgen
abnormal dendritic cell physiology J:138722
abnormal penile erection J:135978
abnormal response to injury J:131314
decreased interleukin-10 secretion J:147023
increased vascular permeability J:131314
Adora2btm1Dgen/Adora2btm1Dgen
involves: 129P2/OlaHsd
altered response to myocardial infarction J:131444
decreased susceptibility to injury J:234143
Adora2btm1Kra/Adora2btm1Kra
involves: 129 * C57BL/6J
abnormal cytokine level J:111715
abnormal inflammatory response J:111715
abnormal interleukin level J:111715
abnormal leukocyte adhesion J:111715
abnormal leukocyte migration J:111715
abnormal tumor necrosis factor level J:111715
normal cardiovascular system phenotype J:111715
decreased interleukin-10 secretion J:111715
enhanced leukocyte tethering or rolling J:111715
increased circulating interleukin-6 level J:111715
Adora2btm1Msit/Adora2btm1Msit
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6
decreased susceptibility to injury J:169155
Adora2btm1Msit/Adora2btm1Msit
Tg(Cdh5-cre)7Mlia/0
involves: FVB/N
normal homeostasis/metabolism phenotype J:203572
Adora2btm1Msit/Adora2btm1Msit
Tg(Sftpc-cre)1Blh/0
involves: C57BL/6 * DBA/2
increased susceptibility to injury J:203572
Adora2btm1Till/Adora2btm1Till
B6.129P2-Adora2btm1Till
abnormal cellular extravasation J:125297
decreased physiological sensitivity to xenobiotic J:125297
normal homeostasis/metabolism phenotype J:125297
impaired adaptive thermogenesis J:125297
increased interleukin-6 secretion J:125297
increased sensitivity to induced morbidity/mortality J:125297
increased susceptibility to type I hypersensitivity reaction J:125297

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/31/2018
MGI 6.12
The Jackson Laboratory