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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ucp1
uncoupling protein 1 (mitochondrial, proton carrier)
MGI:98894
22 phenotypes from 3 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ucp1m1H/Ucp1m1H
C57BL/6J-Ucp1m1H/H
abnormal body temperature homeostasis J:148827
Ucp1tm1b(EUCOMM)Hmgu/Ucp1tm1b(EUCOMM)Hmgu
C57BL/6N-Ucp1tm1b(EUCOMM)Hmgu/Ieg
abnormal lens morphology J:211773
decreased circulating creatinine level J:211773
decreased grip strength J:211773
hypoactivity J:211773
Ucp1tm1Kz/Ucp1tm1Kz
129S1.Cg-Ucptm1Kz
abnormal mitochondrial physiology J:69573
impaired adaptive thermogenesis J:69573
increased brown adipose tissue amount J:69573
Ucp1tm1Kz/Ucp1tm1Kz
(129S1.Cg-Ucptm1Kz x B6.Cg-Ucptm1Kz)F1
abnormal mitochondrial physiology J:69573
normal homeostasis/metabolism phenotype J:69573
Ucp1tm1Kz/Ucp1tm1Kz
B6.Cg-Ucptm1Kz
abnormal lipid homeostasis J:81820
abnormal mitochondrial physiology J:69573
decreased body weight J:81820
decreased circulating free fatty acids level J:81820
decreased circulating thyroxine level J:81820
decreased circulating triglyceride level J:81820
decreased respiratory quotient J:81820
decreased susceptibility to diet-induced obesity J:81820
decreased white adipose tissue amount J:81820
impaired adaptive thermogenesis J:69573
increased body temperature J:81820
increased brown adipose tissue amount J:81820
increased circulating triiodothyronine level J:81820
Ucp1tm1Kz/Ucp1tm1Kz
involves: 129S2/SvPas
abnormal oxygen consumption J:40053
abnormal physiological response to xenobiotic J:40053
decreased oxygen consumption J:62312
decreased susceptibility to diet-induced obesity J:40053
impaired adaptive thermogenesis J:40053
increased brown adipose tissue amount J:40053
Ucp1tm1Kz/Ucp1tm1Kz
involves: 129S2/SvPas * C57BL/6J
abnormal mitochondrial physiology J:57998

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory