Ucp1m1H
Spontaneous Allele Detail
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Symbol: |
Ucp1m1H |
Name: |
uncoupling protein 1 (mitochondrial, proton carrier); mutation 1, Harwell |
MGI ID: |
MGI:3847238 |
Synonyms: |
TRI, UCP1 SNP |
Gene: |
Ucp1 Location: Chr8:84016981-84025081 bp, + strand Genetic Position: Chr8, 39.65 cM
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Alliance: |
Ucp1m1H page
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Allele Type: |
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Spontaneous (Null/knockout) |
Mutation: |
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Single point mutation
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Mutation details: This spontaneous mutation, discovered in the C57BL/6J colony at the Medical Research Council, Harwell, UK, has been identified as a point mutation (C-to-A) in exon 5 that introduces a new acceptor splice site. It is located at position chr2:83295206 (GRCm38) and creates a new CAG splice acceptor site from CCG. This acceptor is used in splicing, removing the first 39 nucleotides of exon 5 from the mRNA and 13 amino-acids from the encoded peptide.
(J:148827)
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Inheritance: |
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Recessive |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ucp1 Mutation: |
46 strains or lines available
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Original: |
J:148827 Moir L, et al., TRI is an allele of Ucp1 and results in thermoregulation defects: Record for Ucp11H. MGI Direct Data Submission. 2009; |
All: |
4 reference(s) |
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