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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Thbs1
thrombospondin 1
MGI:98737
32 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
ApcMin/Apc+
Thbs1tm1Hyn/Thbs1tm1Hyn
involves: C57BL/6J
abnormal intestine morphology J:79641
anemia J:79641
increased carcinoma incidence J:79641
increased intestinal adenoma incidence J:79641
increased tumor incidence J:79641
lordosis J:79641
premature death J:79641
weight loss J:79641
Thbs1tm1Hyn/Thbs1tm1Hyn
Thbs2tm1Bst/Thbs2tm1Bst
involves: 129T2/SvEms * 129X1/SvJ
abnormal blood coagulation J:78876
abnormal skin condition J:78876
abnormal tail morphology J:78876
delayed wound healing J:78876
impaired macrophage chemotaxis J:78876
lordosis J:78876
lung inflammation J:78876
prenatal lethality, incomplete penetrance J:78876
Thbs1tm1Hyn/Thbs1tm1Hyn
Trp53tm1Tyj/Trp53+
involves: 129S2/SvPas * C57BL/6
abnormal tumor morphology J:72391
gastric polyps J:72391
increased adenocarcinoma incidence J:72391
increased adenoma incidence J:72391
increased carcinoma incidence J:72391
increased fibrosarcoma incidence J:72391
increased histiocytic sarcoma incidence J:72391
increased liver adenocarcinoma incidence J:72391
increased lung adenocarcinoma incidence J:72391
increased lymphoma incidence J:72391
increased mammary adenocarcinoma incidence J:72391
increased osteosarcoma incidence J:72391
increased pancreas tumor incidence J:72391
increased papilloma incidence J:72391
increased sarcoma incidence J:72391
increased squamous cell carcinoma incidence J:72391
premature death J:72391
Thbs1tm1Hyn/Thbs1tm1Hyn
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * C57BL/6
increased adenocarcinoma incidence J:72391
increased carcinoma incidence J:72391
increased fibrosarcoma incidence J:72391
increased hemangiosarcoma incidence J:72391
increased histiocytic sarcoma incidence J:72391
increased lymphoma incidence J:72391
increased pancreas tumor incidence J:72391
increased sarcoma incidence J:72391
increased small intestine adenocarcinoma incidence J:72391
premature death J:72391

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory