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Mammalian Phenotype Ontology Annotations
Query Results - Summary
thrombospondin 1
65 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
abnormal heart morphology J:211773
abnormal liver morphology J:211773
abnormal lung morphology J:211773
decreased body length J:211773
decreased circulating insulin level J:211773
enlarged heart J:211773
increased bone mineral content J:211773
either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * C57BL/6)
abnormal cystic duct morphology J:48446
abnormal dermal layer morphology J:48446
abnormal heart ventricle morphology J:48446
abnormal interventricular septum morphology J:48446
abnormal kidney corticomedullary boundary morphology J:48446
abnormal lung morphology J:48446
abnormal lung vasculature morphology J:48446
abnormal pancreas morphology J:48446
bronchial epithelial hyperplasia J:48446
decreased litter size J:46182
dilated gallbladder J:48446
esophagogastric junction metaplasia J:48446
exocrine pancreas hypoplasia J:48446
increased club cell number J:48446
increased eosinophil cell number J:46182
increased leukocyte cell number J:46182
increased lymphocyte cell number J:46182
increased monocyte cell number J:46182
increased neutrophil cell number J:46182
kyphosis J:48446
lordosis J:46182
lung inflammation J:46182, J:48446
pancreas inflammation J:48446
pancreatic islet hyperplasia J:48446
prenatal lethality, incomplete penetrance J:46182
pulmonary alveolar hemorrhage J:48446
reduced fertility J:46182
stomach epithelial hyperplasia J:48446
vascular smooth muscle hyperplasia J:48446
involves: 129S2/SvPas
abnormal hindlimb morphology J:133700
abnormal mitochondrial physiology J:133700
abnormal physiological neovascularization J:133700
abnormal skin physiology J:133700
decreased renal tubule apoptosis J:104708
decreased susceptibility to kidney reperfusion injury J:104708
normal integument phenotype J:133700
involves: 129S2/SvPas * C57BL/6
abnormal conjunctiva goblet cell number J:153126
abnormal cornea morphology J:153126
abnormal corneal epithelium morphology J:153126
abnormal lacrimal gland physiology J:153126
abnormal muscle fiber morphology J:139652
abnormal systemic arterial blood pressure J:148948
normal cellular phenotype J:139652
decreased conjunctiva goblet cell number J:153126
decreased heart rate J:148948
decreased interferon-gamma secretion J:153126
decreased pulse pressure J:148948
decreased regulatory T cell number J:153126
decreased sensitivity to skin irradiation J:139652
increased anti-single stranded DNA antibody level J:153126
increased CD4-positive, alpha beta T cell number J:153126
increased interleukin-17 secretion J:153126
increased lacrimal gland apoptosis J:153126
increased mean systemic arterial blood pressure J:148948
increased systemic arterial diastolic blood pressure J:148948
lacrimal gland inflammation J:153126
microphthalmia J:153126
normal muscle phenotype J:139652
narrow eye opening J:153126

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory