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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ptma
prothymosin alpha
MGI:97803
32 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ptmatm1.1(KOMP)Vlcg/Ptma+
C57BL/6N-Ptmatm1.1(KOMP)Vlcg/Ucd
cornea opacity J:211773
persistence of hyaloid vascular system J:211773
Ptmatm1.1(KOMP)Vlcg/Ptmatm1.1(KOMP)Vlcg
C57BL/6N-Ptmatm1.1(KOMP)Vlcg/Ucd
preweaning lethality, complete penetrance J:211773
Ptmatm1.1Got/Ptma+
involves: C57BL/6J * C57BL/6NTac
abnormal excitatory postsynaptic potential J:240549
abnormal hippocampus neuron morphology J:240549
abnormal learning/memory/conditioning J:240549
abnormal neuron differentiation J:240549
abnormal neuron proliferation J:240549
abnormal passive avoidance behavior J:240549
normal behavior/neurological phenotype J:240549
decreased body temperature J:240549
decreased body weight J:240549
decreased locomotor activity J:240549
impaired cued conditioning behavior J:240549
impaired spatial learning J:240549
increased anxiety-related response J:240549
reduced long-term potentiation J:240549
Ptmatm1.1Got/Ptmatm1.1Got
involves: C57BL/6J * C57BL/6NTac
embryonic lethality, complete penetrance J:240549
Tg(Actb-Ptma)T12Clwu/0
involves: FVB/N
emphysema J:270215
kidney cyst J:128557
Tg(Actb-Ptma)T12Clwu/Tg(Actb-Ptma)T12Clwu
involves: FVB/N
abnormal eating behavior J:128557
decreased birth weight J:128557
emphysema J:128557, J:270215
increased blood urea nitrogen level J:128557
increased kidney weight J:128557
increased liver weight J:128557
kidney epithelium hyperplasia J:128557
polycystic kidney J:128557
postnatal growth retardation J:128557
postnatal lethality, complete penetrance J:128557, J:270215
pulmonary fibrosis J:128557
renal fibrosis J:128557
slow postnatal weight gain J:128557

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory