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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Plaur
plasminogen activator, urokinase receptor
MGI:97612
28 phenotypes from 4 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Plaurem1(IMPC)H/Plaurem1(IMPC)H
C57BL/6NTac-Plaurem1(IMPC)H/H
decreased prepulse inhibition J:211773
increased circulating glucose level J:211773
Plaurtm1Jld/Plaurtm1Jld
B6.129P2-Plaurtm1Jld
chronic inflammation J:164542
normal homeostasis/metabolism phenotype J:164542
increased inflammatory response J:164542
liver fibrosis J:164542
liver inflammation J:164542
trachea inflammation J:164542
Plaurtm1Jld/Plaurtm1Jld
involves: 129P2/OlaHsd * Black Swiss
abnormal macrophage physiology J:26874
normal renal/urinary system phenotype J:26874
Plaurtm1Jld/Plaurtm1Jld
involves: 129P2/OlaHsd * C57BL/6
normal homeostasis/metabolism phenotype J:63134
Plaurtm1Jld/Plaurtm1Jld
involves: 129P2/OlaHsd * C57BL/6J
decreased angiogenesis J:108675
Plaurtm1Mlg/Plaurtm1Mlg
B6.Cg-Plaurtm1Mlg
abnormal brain interneuron morphology J:69135
abnormal cerebral cortex morphology J:69135
abnormal neuronal migration J:69135
normal behavior/neurological phenotype J:81735
decreased exploration in new environment J:81735
increased anxiety-related response J:81735
increased susceptibility to pharmacologically induced seizures J:81735
loss of cortex neurons J:81735
loss of GABAergic neurons J:81735
myoclonus J:81735
Plaurtm1Mlg/Plaurtm1Mlg
involves: 129S2/SvPas * C57BL/6
abnormal cytokine level J:75573
abnormal macrophage physiology J:31253
abnormal neutrophil physiology J:75573, J:91980
normal cardiovascular system phenotype J:82604
normal growth/size/body region phenotype J:31253
normal hematopoietic system phenotype J:31253
impaired neutrophil phagocytosis J:91980
increased susceptibility to bacterial infection J:75573
Tg(CMV-Plaur*)19Lbh/0
FVB/N-Tg(CMV-Plaur*)19Lbh
normal homeostasis/metabolism phenotype J:217443

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory