About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prkcq
protein kinase C, theta
MGI:97601
32 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Crb1rd8/Crb1rd8
Prkcqtm1Litt/Prkcqtm1Litt
B6.129P2-Prkcqtm1Litt 		abnormal ocular fundus morphology J:237977
decreased eye pigmentation J:237977
retina degeneration J:237977
retina detachment J:237977
Pde6brd1/Pde6brd1
Prkcqrpea1/Prkcqrpea1
ABJ/LeJ-Prkcqrpea1/Boc 		abnormal ocular fundus morphology J:237977
buphthalmos J:237977
cataract J:237977
decreased retina ganglion cell number J:237977
decreased retina photoreceptor cell number J:237977
ocular hypertension J:237977
Pde6brd1/Pde6brd1
Prkcqrpea1/Prkcqrpea1
B6.ABJ-Prkcqrpea1 Pde6brd1/Boc 		abnormal ocular fundus morphology J:237977
buphthalmos J:237977
cataract J:237977
decreased retina ganglion cell number J:237977
decreased retina photoreceptor cell number J:237977
ocular hypertension J:237977
retina detachment J:237977
serous retina detachment J:237977
Prkchtm1.2Gasc/Prkchtm1.2Gasc
Prkcqtm1Litt/Prkcqtm1Litt
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL 		abnormal positive T cell selection J:186080
decreased CD4-positive, alpha-beta T cell number J:186080
decreased CD8-positive, alpha-beta T cell number J:186080
decreased DN1 thymic pro-T cell number J:186080
decreased DN4 thymocyte number J:186080
decreased double-negative T cell number J:186080
decreased double-positive T cell number J:186080
decreased T cell proliferation J:186080
normal immune system phenotype J:186080
Prkcqtm1Litt/Prkcqtm1Litt
Tcratm1Mom/Tcratm1Mom
involves: 129P2/OlaHsd * 129S2/SvPas 		decreased interleukin-4 secretion J:135589
decreased T cell proliferation J:135589
normal digestive/alimentary phenotype J:135589
normal immune system phenotype J:135589
Prkcqtm1Litt/Prkcqtm1Litt
Tg(DO11.10)10Dlo/0
involves: 129 * BALB/c * C3H * C57BL/6 		decreased T cell apoptosis J:141930
Prkcqtm1Litt/Prkcqtm1Litt
Tg(Lck-Notch3)#Issc/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		decreased lymphoma incidence J:96010
enlarged chest J:96010
enlarged spleen J:96010
extended life span J:96010
increased spleen weight J:96010
premature death J:96010
Prkcqtm1Litt/Prkcqtm1Litt
Tg(LCKprBCL2L1)12Sjk/0
involves: 129P2/OlaHsd * C57BL/6 		decreased NK T cell number J:141128
normal immune system phenotype J:141128
Prkcqtm1Litt/Prkcqtm1Litt
Tg(TcrLCMV)327Sdz/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		abnormal T cell anergy J:123989
decreased cytotoxic T cell cytolysis J:123989
decreased splenocyte proliferation J:123989
decreased T cell proliferation J:123989
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory