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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
MGI:97383
47 phenotypes from 11 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ntrk1tm1.1Azmo/Ntrk1tm1.1Azmo
involves: 129S2/SvPas
abnormal chemical nociception J:210892
abnormal neurite morphology J:210892
abnormal nociception after inflammation J:210892
abnormal sensory neuron innervation pattern J:210892
abnormal thermosensation J:210892
normal behavior/neurological phenotype J:210892
decreased sensory neuron number J:210892
normal nervous system phenotype J:210892
Ntrk1tm1.1Jcar/Ntrk1tm1.1Jcar
involves: 129S1/Sv * C57BL/6
abnormal sensory neuron physiology J:219326
normal mortality/aging J:219326
Ntrk1tm1Apat/Ntrk1tm1Apat
involves: 129S1/Sv
decreased sensory neuron number J:92099
Ntrk1tm1b(EUCOMM)Wtsi/Ntrk1tm1b(EUCOMM)Wtsi
C57BL/6N-Ntrk1tm1b(EUCOMM)Wtsi/H
preweaning lethality, complete penetrance J:211773
Ntrk1tm1Bbd/Ntrk1tm1Bbd
involves: 129S2/SvPas
abnormal cholinergic neuron morphology J:17194
abnormal digit morphology J:17194
abnormal sympathetic ganglion morphology J:17194
abnormal sympathetic nervous system physiology J:17194
abnormal vibrissae reflex J:17194
blepharoptosis J:17194
corneal opacity J:17194
decreased body size J:17194
increased thermal nociceptive threshold J:17194
miotic pupils J:17194
mottled coat J:17194
postnatal lethality, incomplete penetrance J:17194
premature death J:17194
skin lesions J:17194
small dorsal root ganglion J:17194
small superior cervical ganglion J:17194
small trigeminal ganglion J:17194
ulcerated paws J:17194
unresponsive to tactile stimuli J:17194
Ntrk1tm1Bbd/Ntrk1tm1Bbd
involves: 129S2/SvPas * C57BL/6
normal hearing/vestibular/ear phenotype J:41896
Ntrk1tm1Ddg/Ntrk1tm1Ddg
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:99603
Ntrk1tm1Par/Ntrk1tm1Par
involves: 129S1/Sv * C57BL/6
decreased sensory neuron number J:60927
small dorsal root ganglion J:60927
Ntrk1tm1Tes/Ntrk1tm1Tes
Tg(Tuba1-cre)1Tes/0
involves: 129S1/Sv
abnormal mast cell physiology J:93578
increased B-1 B cell number J:93578
increased IgG1 level J:93578
increased IgG2a level J:93578
increased IgM level J:93578
increased immunoglobulin level J:93578
Ntrk1tm2(Ntrk3)Apat/Ntrk1tm2(Ntrk3)Apat
involves: 129S1/Sv
abnormal pain threshold J:92099
abnormal proprioceptive neuron morphology J:92099
decreased sensory neuron number J:92099
increased muscle spindle number J:92099
premature death J:92099
Ntrk1tm2.1Lfr/Ntrk1tm2.1Lfr
Tg(dlx5a-cre)1Mekk/0
involves: 129 * C57BL/6 * CD-1 * SJL
abnormal behavior J:183467
abnormal innervation J:183467
abnormal response to novel object J:183467
impaired cued conditioning behavior J:183467
Ntrk1tm2.1Tes/Ntrk1tm2.1Tes
B6.129S1(Cg)-Ntrk1tm2.1Tes
abnormal neuron physiology J:209600
abnormal nociception after inflammation J:209600
abnormal thermosensation J:209600
decreased thermal nociceptive threshold J:209600
normal nervous system phenotype J:209600

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory