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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lcat
lecithin cholesterol acyltransferase
MGI:96755
31 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Apoetm1Unc/Apoetm1Unc
Lcattm1Hgc/Lcattm1Hgc
involves: 129P2/OlaHsd * C57BL/6 * DBA
abnormal cholesterol homeostasis J:75567
abnormal circulating protein level J:75567
abnormal lipid homeostasis J:75567
normal homeostasis/metabolism phenotype J:75567
Lcattm1Hgc/Lcattm1Hgc
Ldlrtm1Her/Ldlrtm1Her
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * DBA
abnormal cholesterol homeostasis J:75567, J:89015
abnormal circulating protein level J:75567
abnormal lipid homeostasis J:75567, J:89015
decreased circulating glucose level J:89015
decreased circulating HDL cholesterol level J:75567, J:89015
decreased circulating insulin level J:89015
decreased circulating LDL cholesterol level J:89015
decreased lipoprotein lipase activity J:89015
normal homeostasis/metabolism phenotype J:75567
increased circulating cholesterol level J:75567
increased circulating triglyceride level J:75567, J:89015
increased circulating VLDL cholesterol level J:75567, J:89015
Lcattm1Hgc/Lcattm1Hgc
Tg(SREBP1a)7343Reh/?
involves: 129 * C57BL/6 * C57BL/6J * SJL
abnormal glomerular capillary morphology J:93775
abnormal lipid homeostasis J:93775
abnormal podocyte morphology J:93775
abnormal proximal convoluted tubule morphology J:93775
abnormal renal glomerulus morphology J:93775
abnormal renal tubule morphology J:93775
albuminuria J:93775
decreased circulating HDL cholesterol level J:93775
decreased circulating LDL cholesterol level J:93775
decreased circulating triglyceride level J:93775
enlarged liver J:93775
expanded mesangial matrix J:93775
glomerulosclerosis J:93775
increased circulating cholesterol level J:93775
increased circulating phospholipid level J:93775
increased circulating VLDL cholesterol level J:93775
mesangial cell hyperplasia J:93775
podocyte foot process effacement J:93775
Tg(AlbLCAT)1Jdm/0
involves: FVB/N
decreased circulating triglyceride level J:121992
normal homeostasis/metabolism phenotype J:128254
increased circulating cholesterol level J:121992
increased circulating HDL cholesterol level J:121992
increased susceptibility to atherosclerosis J:128254
Tg(AlbLCAT)1Jdm/0
Tg(APOA1)1Rub/0
involves: C57BL/6 * FVB/N
normal homeostasis/metabolism phenotype J:128254
increased circulating cholesterol level J:121992
increased circulating HDL cholesterol level J:121992
increased circulating LDL cholesterol level J:121992
increased circulating VLDL cholesterol level J:121992
increased susceptibility to atherosclerosis J:128254
Tg(AlbLCAT)1Jdm/0
Tg(APOA1)1Rub/0
Tg(APOA2)3Rub/0
involves: C57BL/6 * FVB/N
increased circulating cholesterol level J:121992
increased circulating HDL cholesterol level J:121992
Tg(AlbLCAT)1Jdm/0
Tg(APOA2)3Rub/0
involves: C57BL/6 * FVB/N
decreased circulating cholesterol level J:121992
decreased circulating HDL cholesterol level J:121992
Tg(LCAT)A31Ssf/0
C57BL/6N-Tg(LCAT)A31Ssf
increased circulating cholesterol level J:118356
increased circulating HDL cholesterol level J:118356
increased circulating phospholipid level J:118356
Tg(LCAT)A31Ssf/Tg(LCAT)A31Ssf
C57BL/6N-Tg(LCAT)A31Ssf
abnormal circulating apolipoprotein E level J:118356
abnormal circulating apolipoprotein level J:118356
increased circulating cholesterol level J:118356
increased circulating HDL cholesterol level J:118356
increased circulating phospholipid level J:118356
Tg(LCAT)T59Ssf/0
C57BL/6N-Tg(LCAT)T59Ssf
increased circulating cholesterol level J:118356
increased circulating HDL cholesterol level J:118356

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory