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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Irf1
interferon regulatory factor 1
MGI:96590
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Del(11Irf1-D11Mit23)1Rub/Del(11Irf1-D11Mit23)1Rub
Tg(A94G6)1Rub/0
involves: 129S6/SvEvTac * C57BL/6J
no abnormal phenotype detected J:60187
Faslpr/Faslpr
Irf1tm1Mak/Irf1+
MRL.Cg-Irf1tm1Mak Faslpr
abnormal skin condition J:114771
glomerulonephritis J:114771
normal immune system phenotype J:114771
increased anti-double stranded DNA antibody level J:114771
increased CD4-positive, alpha beta T cell number J:114771
increased urine protein level J:114771
premature death J:114771
Faslpr/Faslpr
Irf1tm1Mak/Irf1tm1Mak
MRL.Cg-Irf1tm1Mak Faslpr
abnormal cell physiology J:114771
abnormal cytokine secretion J:114771
decreased anti-double stranded DNA antibody level J:114771
glomerulonephritis J:114771
normal homeostasis/metabolism phenotype J:114771
normal immune system phenotype J:114771
increased CD4-positive, alpha beta T cell number J:114771
normal integument phenotype J:114771
premature death J:114771
Irf1tm1Mak/Irf1tm1Mak
Tg(HRAS)2Jic/?
involves: 129S2/SvPas * BALB/c * C57BL/6
increased hemangiosarcoma incidence J:55418
increased tumor incidence J:55418
Irf1tm1Mak/Irf1tm1Mak
Trp53tm1Sia/Trp53tm1Sia
involves: 129S2/SvPas * C57BL/6 * CBA
increased hemangiosarcoma incidence J:55418
increased lymphoma incidence J:55418
increased teratoma incidence J:55418
increased tumor incidence J:55418
premature death J:55418

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory