Hoxb3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hoxb3
homeobox B3
MGI:96184

32 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hoxa3^tm1Mrc/Hoxa3⁺ Hoxb3^tm1Mrc/Hoxb3^tm1Mrc involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J	ectopic parathyroid gland	J:46523
	ectopic thymus	J:46523
Hoxa3^tm1Mrc/Hoxa3^tm1Mrc Hoxb3^tm1Mrc/Hoxb3^tm1Mrc involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J	abnormal cervical atlas morphology	J:45337
	abnormal cervical axis morphology	J:45337
	abnormal cervical vertebrae morphology	J:45337
	abnormal cricoid cartilage morphology	J:45337
	abnormal hyoid bone greater horn morphology	J:45337
	abnormal hyoid bone lesser horn morphology	J:45337
	abnormal hyoid bone morphology	J:45337
	abnormal laryngeal cartilage morphology	J:45337
	abnormal occipital bone morphology	J:45337
	abnormal supraoccipital bone morphology	J:45337
	abnormal thyroid gland isthmus morphology	J:46523
	abnormal ultimobranchial body morphology	J:46523
	absent thyroid gland isthmus	J:46523
	absent ultimobranchial body	J:46523
	decreased sensory neuron number	J:88581
	fusion of atlas and occipital bones	J:45337
	neonatal lethality, complete penetrance	J:45337
	persistent ultimobranchial bodies	J:46523
	small cricoid cartilage	J:45337
	small exoccipital bone	J:45337
	thyroid cartilage hypoplasia	J:45337
Hoxa3^tm3Mrc/Hoxa3^tm3Mrc Hoxb3^tm1Mrc/Hoxb3^tm1Mrc involves: 129S4/SvJae	abnormal somatic motor system morphology	J:86041
Hoxb3^tm1.1Karl/Hoxb3^tm1.1Karl Hoxb4^tm2.1Karl/Hoxb4^tm2.1Karl involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:83563
Hoxb3^tm1Mrc/Hoxb3^tm1Mrc Hoxd3^tm1Mrc/Hoxd3^tm1Mrc involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J	abnormal cervical atlas morphology	J:19447
	abnormal cervical vertebrae morphology	J:19447, J:45337
	abnormal hyoid bone morphology	J:45337
	abnormal inferior horn of thyroid cartilage morphology	J:19447
	abnormal thyroid cartilage morphology	J:19447
	abnormal ultimobranchial body morphology	J:46523
	absent cervical atlas	J:19447
	fusion of glossopharyngeal and vagus nerve	J:45337
	hyoid bone hypoplasia	J:19447
	neonatal lethality, incomplete penetrance	J:45337
	postnatal lethality, complete penetrance	J:45337

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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