73 phenotypes from 7 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hhextm1Cwb/Hhextm1Cwb involves: 129X1/SvJ * C57BL/6J	abnormal atrioventricular cushion morphology	J:93580
	abnormal atrioventricular valve morphology	J:93580
	abnormal blood vessel morphology	J:93580
	abnormal cardiac epithelial to mesenchymal transition	J:93580
	abnormal conotruncal ridge morphology	J:93580
	abnormal forebrain development	J:93580
	abnormal liver development	J:93580
	abnormal myocardial trabeculae morphology	J:93580
	abnormal thyroid gland development	J:93580
	abnormal vasculogenesis	J:93580
	absent liver	J:93580
	conotruncal ridge hyperplasia	J:93580
	decreased forebrain size	J:93580
	decreased heart right ventricle size	J:93580
	double outlet right ventricle	J:93580
	edema	J:93580
	embryonic lethality during organogenesis, complete penetrance	J:93580
	heart right ventricle outflow tract stenosis	J:93580
	increased atrioventricular cushion size	J:93580
	pericardial edema	J:93580
	thin myocardium compact layer	J:93580
	thin ventricular wall	J:93580
	vascular smooth muscle hypoplasia	J:93580
	ventricular septal defect	J:93580
Hhextm1Cwb/Hhextm2Cwb Tg(Alb1-cre)1Khk/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal bile duct development	J:124126
	abnormal liver morphology	J:124126
	liver cyst	J:124126
Hhextm1Cwb/Hhextm2Cwb Tg(Foxa3-cre)1Khk/? involves: 129X1/SvJ * C57BL/6 * DBA * SJL	abnormal extrahepatic bile duct morphology	J:124126
	abnormal hepatic duct morphology	J:124126
	abnormal intrahepatic bile duct morphology	J:124126
	abnormal liver morphology	J:124126
	absent gallbladder	J:124126
	biliary cyst	J:124126
	liver cyst	J:124126
	liver hypoplasia	J:124126
	prenatal lethality, complete penetrance	J:124126
Hhextm1Jomb/Hhextm1Jomb involves: 129P2/OlaHsd * C57BL/6	abnormal embryo development	J:149792
	prenatal lethality, complete penetrance	J:149792
Hhextm1Ngu/Hhextm1Ngu involves: 129/Sv * C57BL/6	abnormal hepatocyte morphology	J:65105
	abnormal liver bud morphology	J:65105
	abnormal liver development	J:65105
	abnormal monocyte differentiation	J:65105
	embryonic lethality during organogenesis, complete penetrance	J:65105
	impaired hematopoiesis	J:65105
Hhextm1Rbe/Hhextm1Rbe B6.129P2-Hhextm1Rbe	abnormal thyroid gland development	J:95017
Hhextm1Rbe/Hhextm1Rbe involves: 129P2/OlaHsd * C57BL/6	abnormal anterior definitive endoderm morphology	J:62027
	abnormal first pharyngeal arch morphology	J:62027
	abnormal forebrain development	J:62027
	abnormal hepatic diverticulum morphology	J:62027
	abnormal hepatoblast migration	J:62027
	abnormal medial ganglionic eminence morphology	J:62027
	abnormal nasal placode morphology	J:62027
	abnormal optic stalk morphology	J:62027
	abnormal optic vesicle formation	J:62027
	abnormal pericardial cavity morphology	J:62027
	abnormal telencephalon development	J:62027
	abnormal thyroid gland development	J:62027
	abnormal thyroid gland morphology	J:62027
	absent embryonic telencephalon	J:62027
	absent forebrain	J:62027
	absent liver	J:62027
	absent nasal placodes	J:62027
	absent Rathke's pouch	J:62027
	anophthalmia	J:62027
	decreased forebrain size	J:62027
	embryonic growth retardation	J:62027
	embryonic lethality during organogenesis, incomplete penetrance	J:62027
	fused first pharyngeal arch	J:62027
	lethality throughout fetal growth and development, complete penetrance	J:62027
	rostral body truncation	J:62027
	small embryonic telencephalon	J:62027
Hhextm2Cwb/Hhextm2Cwb Tg(Alb1-cre)1Khk/? involves: 129S1/Sv * C57BL/6 * SJL	liver cyst	J:124126
Tg(ITGAL-Hhex)2Hro/0 C3HeB/FeJ-Tg(ITGAL-Hhex)2Hro	abnormal common myeloid progenitor cell morphology	J:80777
	abnormal definitive hematopoiesis	J:80777
	abnormal double-negative T cell morphology	J:80777
	abnormal thymus corticomedullary boundary morphology	J:80777
	decreased double-positive T cell number	J:80777
	decreased leukocyte cell number	J:80777
	decreased lymphocyte cell number	J:80777
	decreased T cell number	J:80777
	increased CD8-positive, alpha-beta T cell number	J:80777
	increased erythroid progenitor cell number	J:80777
	thymus hypoplasia	J:80777
Tg(Lck-Hhex)1Hro/0 C3HeB/FeJ-Tg(Lck-Hhex)1Hro	abnormal double-negative T cell morphology	J:80777
	decreased double-positive T cell number	J:80777
	decreased leukocyte cell number	J:80777
	decreased lymphocyte cell number	J:80777
	decreased T cell number	J:80777
	increased CD8-positive, alpha-beta T cell number	J:80777
	thymus hyperplasia	J:80777