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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Glul
glutamate-ammonia ligase
MGI:95739
36 phenotypes from 5 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Glultm1.1Geno/Glultm1.1Geno
B6J.Cg-Glultm1.1Geno 		no abnormal phenotype detected J:221031
Glultm1.1Geno/Glultm1.1Geno
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: C57BL/6 * C57BL/6J * DBA 		abnormal fear-related response J:221031
normal homeostasis/metabolism phenotype J:221031
hyperactivity J:221031
increased circulating ammonia level J:221031
normal liver/biliary system phenotype J:221031
oxidative stress J:221031
premature death J:221031
Glultm1.1Ncd/Glultm1.1Ncd
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Glultm1.1Ncd Emx1tm1(cre)Krj 		abnormal blood vessel physiology J:272643
abnormal brain vasculature morphology J:272643
abnormal locomotor activation J:272643
astrocytosis J:272643
decreased anxiety-related response J:272643
decreased aspartic acid level J:272643
decreased gamma-aminobutyric acid level J:272643
decreased glutamic acid level J:272643
decreased glutamine level J:272643
decreased locomotor activity J:272643
decreased vertical activity J:272643
hippocampus pyramidal cell degeneration J:272643
increased locomotor activity J:272643
neurodegeneration J:272643
premature death J:272643
seizures J:272643
Glultm1Whla/Glultm1Whla
FVBHanHsd.129P2-Glultm1Whla 		embryonic lethality before implantation, incomplete penetrance J:122377
embryonic lethality, complete penetrance J:122377
Glultm1Whla/Glultm2Whla
involves: 129P2/OlaHsd 		embryonic lethality between somite formation and embryo turning, complete penetrance J:122377
Glultm3Whla/Glultm1Whla
Tg(Ckmm-cre)5Khn/0
involves: 129P2/OlaHsd * FVB 		abnormal amino acid level J:161082
abnormal ammonia homeostasis J:161082
abnormal postnatal growth J:161082
decreased circulating glutamine level J:161082
decreased glutamine level J:161082
Glultm3Whla/Glultm1Whla
Tg(GFAP-cre)25Mes/0
involves: 129P2/OlaHsd * FVB/N 		abnormal amino acid level J:162067
abnormal ammonia homeostasis J:162067
abnormal brain morphology J:162067
abnormal food intake J:162067
decreased circulating glucose level J:162067
decreased glutamine level J:162067
increased glycine level J:162067
postnatal lethality, complete penetrance J:162067
Glultm3Whla/Glultm3Whla
Tg(Ckmm-cre)5Khn/0
involves: 129P2/OlaHsd * FVB 		abnormal amino acid level J:161082
abnormal ion homeostasis J:161082
abnormal postnatal growth J:161082
Glultm3Whla/Glultm3Whla
Tg(GFAP-cre)25Mes/0
involves: 129P2/OlaHsd * FVB/N 		abnormal amino acid level J:162067
abnormal ammonia homeostasis J:162067
abnormal brain morphology J:162067
abnormal food intake J:162067
decreased circulating glucose level J:162067
decreased glutamine level J:162067
increased glycine level J:162067
postnatal lethality, complete penetrance J:162067
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory