93 phenotypes from 7 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
En1tm2(cre)Gld/En1+ Gli2tm1Alj/Gli2tm6Alj involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster	abnormal cerebellar granule layer morphology	J:108507
	abnormal cerebellar lobule formation	J:108507
	abnormal cerebellar molecular layer	J:108507
	abnormal cerebellar Purkinje cell layer	J:108507
	abnormal cerebellum anterior vermis morphology	J:108507
	abnormal cerebellum external granule cell layer morphology	J:108507
	abnormal cerebellum vermis morphology	J:108507
	abnormal gait	J:108507
	decreased body size	J:108507
	impaired balance	J:108507
	normal nervous system phenotype	J:108507
	small cerebellum	J:108507
	thin external granule cell layer	J:108507
	tremors	J:108507
Gli2tm1Alj/Gli2+ involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal neural tube morphology	J:152259
Gli2tm1Alj/Gli2tm1Alj either: (involves: 129S1/Sv * 129X1/Sv) or (involves: 129S1/Sv * 129X1/Sv * CD-1)	abnormal basioccipital bone morphology	J:38381
	abnormal basisphenoid bone morphology	J:38381
	abnormal frontal bone morphology	J:38381
	abnormal head shape	J:38381
	abnormal long bone morphology	J:38381
	abnormal palatal shelf elevation	J:38381
	abnormal palatal shelf fusion at midline	J:38381
	abnormal parietal bone morphology	J:38381
	abnormal spine curvature	J:38381
	abnormal vertebral body morphology	J:38381
	absent intervertebral disk	J:38381
	absent lower incisors	J:38381
	absent maxillary shelf	J:38381
	absent palatine bone horizontal plate	J:38381
	absent presphenoid bone	J:38381
	absent tympanic ring	J:38381
	absent upper incisors	J:38381
	bowed radius	J:38381
	cleft secondary palate	J:38381
	decreased embryo size	J:38381
	delayed bone ossification	J:38381
	edema	J:38381
	increased rib number	J:38381
	microcephaly	J:38381
	perinatal lethality, complete penetrance	J:38381
	short femur	J:38381
	short fibula	J:38381
	short humerus	J:38381
	short limbs	J:38381
	short maxilla	J:38381
	short radius	J:38381
	short sternum	J:38381
	short tibia	J:38381
	short ulna	J:38381
	small mandible	J:38381
Gli2tm1Alj/Gli2tm1Alj involves: 129S1/Sv * 129X1/SvJ	abnormal neuron differentiation	J:112802
Gli2tm1Alj/Gli2tm1Alj involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * FVB/N	abnormal epiphyseal plate morphology	J:153743
	absent temporomandibular joint disk	J:153743
	decreased chondrocyte number	J:153743
	small mandibular condyloid process	J:153743
Gli2tm1Alj/Gli2tm1Alj involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal esophageal smooth muscle morphology	J:49603
	abnormal esophagus development	J:49603
	abnormal foregut morphology	J:49603
	abnormal lung development	J:49603
	abnormal neural tube morphology	J:152259
	abnormal right lung morphology	J:49603
	abnormal tracheal cartilage morphology	J:49603
	decreased lung weight	J:49603
	decreased mesenchymal cell proliferation involved in lung development	J:49603
	esophagus hypoplasia	J:49603
	esophagus stenosis	J:49603
	increased type II pneumocyte number	J:49603
	pulmonary hypoplasia	J:49603
	small lung	J:49603
	small lung saccule	J:49603
	thick lung-associated mesenchyme	J:49603
	trachea hypoplasia	J:49603
	trachea stenosis	J:49603
Gli2tm1Alj/Gli2tm1Alj involves: 129S1/Sv * 129X1/SvJ * Swiss Webster	abnormal cerebellar foliation	J:94461
	perinatal lethality, complete penetrance	J:94461
	reduced cerebellar foliation	J:94461
	small cerebellum	J:94461
	thin external granule cell layer	J:94461
Gli2tm1Alj/Gli2tm2.1Alj either: (involves: 129) or (involves: 129 * Black Swiss)	abnormal notochord morphology	J:73074
	abnormal spinal cord morphology	J:73074
	abnormal ventral interneuron 3 morphology	J:73074
	absent floor plate	J:73074
	absent right lung accessory lobe	J:73074
	persistence of notochord tissue	J:73074
	small lung	J:73074
Gli2tm1Alj/Gli2tm6.1Alj involves: 129/Sv * C57BL/6 * SJL	abnormal cerebellar foliation	J:108507
	abnormal developmental patterning	J:108507
	abnormal rostral-caudal axis patterning	J:108507
	hydrocephaly	J:108507
	perinatal lethality, complete penetrance	J:108507
	reduced cerebellar foliation	J:108507
	small cerebellum	J:108507
	thin external granule cell layer	J:108507
Gli2tm1Alj/Gli2tm6Alj Tg(Nes-cre)1Kln/0 involves: 129/Sv * C57BL/6 * SJL * Swiss Webster	abnormal cerebellar foliation	J:108507
Gli2tm2.1(Gli3)Blnw/Gli2tm2.1(Gli3)Blnw involves: 129S6/SvEvTac * C57BL/6	decreased body size	J:169530
Gli2tm2.1Alj/Gli2tm2.1Alj either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)	abnormal notochord morphology	J:73074
	abnormal spinal cord morphology	J:73074
	abnormal ventral interneuron 3 morphology	J:73074
	absent floor plate	J:73074
	absent right lung accessory lobe	J:73074
	persistence of notochord tissue	J:73074
	small lung	J:73074
Gli2tm2.1Alj/Gli2tm2.1Alj involves: 129S6/SvEvTac * Black Swiss * Swiss Webster	perinatal lethality	J:112460
	normal reproductive system phenotype	J:112460
Gli2tm2.1Alj/Gli2tm2.1Alj involves: 129S6/SvEvTac * C57BL/6 * Swiss Webster	abnormal floor plate morphology	J:169530
	abnormal motor neuron morphology	J:169530
Gli2tm6.1Alj/Gli2tm6.1Alj involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * SJL	abnormal cerebellar foliation	J:108507
	abnormal developmental patterning	J:108507
	abnormal rostral-caudal axis patterning	J:108507
	hydrocephaly	J:108507
	perinatal lethality, complete penetrance	J:108507
	reduced cerebellar foliation	J:108507
	small cerebellum	J:108507
	thin external granule cell layer	J:108507
Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+ Nkx3-2tm1(cre)Wez/Nkx3-2+ involves: 129S7/SvEvBrd	normal digestive/alimentary phenotype	J:199664
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+ Tg(Col2a1-cre)3Amc/0 involves: 129X1/SvJ	abnormal cartilage development	J:154905
	abnormal long bone epiphyseal plate proliferative zone	J:154905
	decreased body size	J:154905
	decreased length of long bones	J:154905
	decreased width of hypertrophic chondrocyte zone	J:154905
	increased width of hypertrophic chondrocyte zone	J:154905