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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gfap
glial fibrillary acidic protein
MGI:95697
29 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Del(9Hspb2-Cryab)1Wawr/Del(9Hspb2-Cryab)1Wawr
Gfaptm2Mes/Gfap+
involves: 129S4/SvJae * 129S7/SvEvBrd 		normal mortality/aging J:146191
Gfaptm1Pkny/Gfaptm1Pkny
Ppt1tm1Hof/Ppt1tm1Hof
Vimtm1Cba/Vimtm1Cba
involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac * C57BL/6 		abnormal brain morphology J:177265
abnormal cytokine level J:177265
abnormal nervous system morphology J:177265
abnormal visual cortex morphology J:177265
brain atrophy J:177265
brain inflammation J:177265
decreased brain weight J:177265
hippocampal neuron degeneration J:177265
neurodegeneration J:177265
premature death J:177265
thin cerebral cortex J:177265
Gfaptm1Pkny/Gfaptm1Pkny
Vimtm1Cba/Vimtm1Cba
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		abnormal dentate gyrus morphology J:106195
abnormal neuron differentiation J:106195
Gfaptm1Pkny/Gfaptm1Pkny
Vimtm1Cba/Vimtm1Cba
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		abnormal astrocyte morphology J:125659
abnormal astrocyte physiology J:125659
abnormal spinal cord morphology J:124385
astrocytosis J:124385
decreased inflammatory response J:123278
decreased neuron apoptosis J:123278
gliosis J:123278
increased vasodilation J:124385
intracranial hemorrhage J:124385
normal nervous system phenotype J:124385
normal vision/eye phenotype J:123278
Gfaptm2Mes/Gfap+
Tg(GFAP)10Mes/0
involves: 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N 		abnormal astrocyte morphology J:114689
premature death J:114689
seizures J:114689
Gfaptm2Mes/Gfap+
Tg(GFAP)10Mes/0
involves: 129S7/SvEvBrd * FVB/N 		abnormal hippocampus morphology J:146191
premature death J:146191
Gfaptm2Mes/Gfap+
Tg(GFAP)10Mes/0
Tg(GFAP-CRYAB)141.6Mes/0
involves: 129S4/SvJae * 129S7/SvEvBrd * FVB/N 		abnormal hippocampus morphology J:146191
normal mortality/aging J:146191
Gfaptm2Mes/Gfap+
Tg(GFAP-CRYAB)141.6Mes/0
involves: 129S7/SvEvBrd * FVB/N 		abnormal cell physiology J:146191
Gfaptm4Ito/Gfaptm4Ito
Vimtm1Cba/Vimtm1Cba
either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6) 		abnormal astrocyte morphology J:78341
abnormal CNS glial cell morphology J:78341
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory