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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cidec
cell death-inducing DFFA-like effector c
MGI:95585
56 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cidectm1.1Gonz/Cidectm1.1Gonz
B6N.Cg-Cidectm1.1Gonz 		no abnormal phenotype detected J:226899
Cidectm1.1Gonz/Cidectm1.2Gonz
Tg(Fabp4-cre)#Abel/?
B6N.Cg-Cidectm1.1Gonz/Cidectm1.2Gonz Tg(Fabp4-cre)#Abel 		abnormal adaptive thermogenesis J:226899
abnormal circulating lipid level J:226899
abnormal white adipose tissue morphology J:226899
abnormal white adipose tissue physiology J:226899
abnormal white fat cell morphology J:226899
decreased percent body fat/body weight J:226899
decreased respiratory quotient J:226899
decreased susceptibility to diet-induced obesity J:226899
decreased white adipose tissue amount J:226899
decreased white fat cell size J:226899
hepatic steatosis J:226899
hyperactivity J:226899
increased adipocyte glucose uptake J:226899
increased brown adipose tissue amount J:226899
increased circulating alanine transaminase level J:226899
increased circulating free fatty acids level J:226899
increased circulating insulin level J:226899
increased circulating triglyceride level J:226899
increased energy expenditure J:226899
increased lean body mass J:226899
increased oxygen consumption J:226899
insulin resistance J:226899
Cidectm1b(EUCOMM)Wtsi/Cidectm1b(EUCOMM)Wtsi
C57BL/6N-Cidectm1b(EUCOMM)Wtsi/Ieg 		abnormal auditory brainstem response J:211773
abnormal optic disk morphology J:211773
decreased circulating alkaline phosphatase level J:211773
decreased total body fat amount J:211773
increased circulating cholesterol level J:211773
increased fasting circulating glucose level J:211773
increased lean body mass J:211773
increased mean corpuscular volume J:211773
Cidectm1Maka/Cidectm1Maka
B6.129P2-Cidectm1Maka 		abnormal brown adipose tissue morphology J:140863
abnormal white adipose tissue morphology J:140863
decreased circulating glucose level J:140863
decreased circulating leptin level J:140863
decreased subcutaneous adipose tissue amount J:140863
decreased susceptibility to age related obesity J:140863
decreased susceptibility to diet-induced hepatic steatosis J:140863
decreased susceptibility to diet-induced obesity J:140863
decreased white adipose tissue amount J:140863
enhanced lipolysis J:140863
improved glucose tolerance J:140863
increased energy expenditure J:140863
increased oxygen consumption J:140863
increased respiratory quotient J:140863
Cidectm1Pli/Cidectm1Pli
Not Specified 		abnormal blood homeostasis J:140122
abnormal brown adipose tissue morphology J:140122
abnormal fat cell morphology J:140122
abnormal fat pad morphology J:140122
abnormal gonadal fat pad morphology J:140122
decreased circulating free fatty acids level J:140122
decreased circulating ketone body level J:140122
decreased circulating leptin level J:140122
decreased circulating triglyceride level J:140122
decreased gonadal fat pad weight J:140122
decreased inguinal fat pad weight J:140122
decreased mesenteric fat pad weight J:140122
decreased retroperitoneal fat pad weight J:140122
decreased subcutaneous adipose tissue amount J:140122
decreased total body fat amount J:140122
enhanced lipolysis J:140122
impaired adaptive thermogenesis J:140122
improved glucose tolerance J:140122
increased body temperature J:140122
increased food intake J:140122
increased insulin sensitivity J:140122
increased oxygen consumption J:140122
normal integument phenotype J:215366
normal vision/eye phenotype J:215366
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory