About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cfh
complement component factor h
MGI:88385
66 phenotypes from 4 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cfhtm1.1Song/Cfhtm1.1Song
involves: C57BL/6
abnormal behavior J:240426
abnormal blood coagulation J:240426
abnormal blood homeostasis J:240426
abnormal brain thrombosis J:240426
abnormal glomerular capillary endothelium morphology J:240426
abnormal glomerular capillary morphology J:240426
abnormal glomerular capillary thrombosis J:240426
abnormal glomerular mesangium morphology J:240426
abnormal hepatic portal vein thrombosis J:240426
abnormal kidney morphology J:240426
abnormal kidney thrombosis J:240426
abnormal kidney vasculature morphology J:240426
abnormal kidney venous thrombosis J:240426
abnormal lung thrombosis J:240426
abnormal renal glomerulus morphology J:240426
abnormal retina morphology J:240426
abnormal retina vasculature morphology J:240426
abnormal thrombosis J:240426
anemia J:240426
artery occlusion J:240426
brain ischemia J:240426
circling J:240426
decreased body size J:240426
decreased circulating complement protein level J:240426
decreased complement C5 level J:240426
decreased hemoglobin content J:240426
decreased serum complement activity J:240426
expanded mesangial matrix J:240426
hindlimb paralysis J:240426
impaired muscle relaxation J:240426
increased blood urea nitrogen level J:240426
increased creatine level J:240426
increased susceptilbility to retina ischemic injury J:240426
intracerebral hemorrhage J:240426
premature death J:240426
reticulocytosis J:240426
retina detachment J:240426
thrombocytopenia J:240426
white pupil J:240426
Cfhtm1a(EUCOMM)Wtsi/Cfhtm1a(EUCOMM)Wtsi
C57BL/6N-Cfhtm1a(EUCOMM)Wtsi/Wtsi
increased mean corpuscular hemoglobin J:175295
Cfhtm1Mbo/Cfh+
involves: 129/Sv * C57BL/6
decreased circulating complement protein level J:78193
Cfhtm1Mbo/Cfhtm1Mbo
B6.129-Cfhtm1Mbo
abnormal Bruch membrane morphology J:125991
abnormal retina layer morphology J:125991
abnormal retina morphology J:125991, J:203471
abnormal retina photoreceptor morphology J:125991
abnormal retina pigment epithelium morphology J:125991
abnormal retina rod bipolar cell morphology J:125991
amyloid beta deposits J:203471
decreased a-wave amplitude J:125991
decreased b-wave amplitude J:125991
decreased visual acuity J:125991
disorganized photoreceptor outer segment J:125991
Cfhtm1Mbo/Cfhtm1Mbo
involves: 129
abnormal complement protein level J:125860
decreased circulating complement protein level J:125860, J:131403
glomerulonephritis J:131403
renal glomerular protein deposits J:131403
Cfhtm1Mbo/Cfhtm1Mbo
involves: 129/Sv * C57BL/6
abnormal kidney capillary morphology J:78193
abnormal renal glomerulus basement membrane morphology J:78193
abnormal renal glomerulus morphology J:78193
albuminuria J:78193
decreased circulating complement protein level J:78193
expanded mesangial matrix J:78193
glomerulonephritis J:78193
hematuria J:78193
increased mesangial cell number J:78193
increased susceptibility to type III hypersensitivity reaction J:78193
increased urine protein level J:78193
mesangial cell interposition J:78193
premature death J:78193
renal glomerular immunoglobulin deposits J:78193
renal glomerular protein deposits J:78193
Cfhtm1Mbo/Cfhtm1Mbo
Tg(CAG-Cfh*)#Mcp/0
involves: 129/Sv * C57BL/6 * CBA
abnormal circulating complement protein level J:125860
abnormal complement protein level J:125860
abnormal kidney thrombosis J:125860
anasarca J:125860
hematuria J:125860
increased blood urea nitrogen level J:125860
kidney failure J:125860
premature death J:125860
schistocytosis J:125860
thrombocytopenia J:125860

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory