F2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F2
coagulation factor II
MGI:88380

37 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F2^{tm1b(EUCOMM)Hmgu}/F2⁺ C57BL/6N-F2^{tm1b(EUCOMM)Hmgu}/H	decreased bone mineral content	J:211773
	decreased exploration in new environment	J:211773
	decreased lean body mass	J:211773
	decreased mean corpuscular volume	J:211773
	increased circulating fructosamine level	J:211773
	increased circulating serum albumin level	J:211773
	increased total body fat amount	J:211773
	tremors	J:211773
F2^{tm1b(EUCOMM)Hmgu}/F2^{tm1b(EUCOMM)Hmgu} C57BL/6N-F2^{tm1b(EUCOMM)Hmgu}/H	preweaning lethality, incomplete penetrance	J:211773
F2^tm1Jes/F2^tm1Jes involves: 129P2/OlaHsd * C57BL/6J	abnormal vitelline vasculature morphology	J:48274
	embryonic lethality, incomplete penetrance	J:48274
	hemorrhage	J:48274
	intracranial hemorrhage	J:48274
	lethality throughout fetal growth and development, incomplete penetrance	J:48274
	lethality, incomplete penetrance	J:48274
	neonatal lethality, complete penetrance	J:48274
	pallor	J:48274
F2^tm1Sjd/F2⁺ involves: 129P2/OlaHsd	normal homeostasis/metabolism phenotype	J:174629
F2^tm1Sjd/F2^tm1Sjd involves: 129P2/OlaHsd * Black Swiss	abnormal visceral yolk sac morphology	J:48273
	decreased embryo size	J:48273
	distended pericardium	J:48273
	embryo tissue necrosis	J:48273
	embryonic growth arrest	J:48273
	embryonic lethality during organogenesis, incomplete penetrance	J:48273
	hemopericardium	J:48273
	hemorrhage	J:48273
	impaired blood coagulation	J:48273
	intestinal hemorrhage	J:48273
	neonatal lethality, complete penetrance	J:48273
	pale yolk sac	J:48273
	postnatal lethality, complete penetrance	J:48273
	purpura	J:48273
F2^tm2Jld/F2⁺ B6.129P2-F2^tm2Jld	abnormal circulating protein level	J:174629
	decreased susceptibility to endotoxin shock	J:174629
	decreased susceptibility to induced thrombosis	J:174629
	increased bleeding time	J:174629
F2^tm2Jld/F2⁺ involves: 129P2/OlaHsd * C57BL/6 * DBA/2J	decreased susceptibility to induced arthritis	J:174629
F2^tm2Jld/F2^tm2Jld B6.129P2-F2^tm2Jld	internal hemorrhage	J:174629
	postnatal lethality, complete penetrance	J:174629
	subcutaneous hemorrhage	J:174629

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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