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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
F2
coagulation factor II
MGI:88380
40 phenotypes from 5 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
F2tm1b(EUCOMM)Hmgu/F2+
C57BL/6N-F2tm1b(EUCOMM)Hmgu/H
tremors J:211773
F2tm1b(EUCOMM)Hmgu/F2tm1b(EUCOMM)Hmgu
C57BL/6N-F2tm1b(EUCOMM)Hmgu/H
preweaning lethality, incomplete penetrance J:211773
F2tm1Jes/F2tm1Jes
involves: 129P2/OlaHsd * C57BL/6J
abnormal vitelline vasculature morphology J:48274
embryonic lethality, incomplete penetrance J:48274
hemorrhage J:48274
intracranial hemorrhage J:48274
lethality throughout fetal growth and development, incomplete penetrance J:48274
lethality, incomplete penetrance J:48274
neonatal lethality, complete penetrance J:48274
pallor J:48274
F2tm1Jld/F2tm1Jld
B6.129P2-F2tm1Jld
no abnormal phenotype detected J:144572
F2tm1Jld/F2tm1Jld
Tg(Mx1-cre)1Cgn/0
B6.Cg-F2tm1Jld Tg(Mx1-cre)1Cgn
increased susceptibility to bacterial infection J:144572
F2tm1Jld/F2tm1Sjd
involves: 129P2/OlaHsd * C57BL/6J
abnormal blood coagulation J:144572
increased bleeding time J:144572
F2tm1Jld/F2tm1Sjd
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA
abnormal blood coagulation J:144572
abnormal heart morphology J:144572
cardiac fibrosis J:144572
cerebellum hemorrhage J:144572
gastrointestinal hemorrhage J:144572
genital hemorrhage J:144572
heart hemorrhage J:144572
hemorrhage J:144572
hemothorax J:144572
increased bleeding time J:144572
intracranial hemorrhage J:144572
petechiae J:144572
premature death J:144572
skin hemorrhage J:144572
spinal hemorrhage J:144572
F2tm1Sjd/F2+
involves: 129P2/OlaHsd
normal homeostasis/metabolism phenotype J:174629
F2tm1Sjd/F2tm1Sjd
involves: 129P2/OlaHsd * Black Swiss
abnormal blood coagulation J:48273
abnormal visceral yolk sac morphology J:48273
decreased embryo size J:48273
distended pericardium J:48273
embryo tissue necrosis J:48273
embryonic growth arrest J:48273
embryonic lethality during organogenesis, incomplete penetrance J:48273
hemopericardium J:48273
hemorrhage J:48273
neonatal lethality, complete penetrance J:48273
pale yolk sac J:48273
postnatal lethality, complete penetrance J:48273
purpura J:48273
F2tm2Jld/F2+
B6.129P2-F2tm2Jld
abnormal circulating protein level J:174629
decreased platelet aggregation J:174629
decreased susceptibility to endotoxin shock J:174629
increased bleeding time J:174629
F2tm2Jld/F2+
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J
decreased susceptibility to induced arthritis J:174629
F2tm2Jld/F2tm2Jld
B6.129P2-F2tm2Jld
hemorrhage J:174629
postnatal lethality, complete penetrance J:174629

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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory