Agap2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
MGI:3580016

18 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agap2^tm1.1Kye/Agap2^tm1.1Kye involves: C57BL/6	abnormal mammary gland alveolus morphology	J:158376
	abnormal mammary gland growth during lactation	J:158376
	abnormal milk composition	J:158376
	decreased mammary gland epithelial cell proliferation	J:158376
	increased mammary gland apoptosis	J:158376
	lactation failure	J:158376
Agap2^tm1.1Kye/Agap2^tm1.1Kye Not Specified	abnormal gluconeogenesis	J:174775
	hyperglycemia	J:174775
	increased insulin sensitivity	J:174775
	insulin resistance	J:174775
Agap2^tm1Kye/Agap2^tm1Kye Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA/2	abnormal gluconeogenesis	J:174775
	decreased circulating triglyceride level	J:174775
	decreased liver cholesterol level	J:174775
	decreased liver free fatty acids level	J:174775
	decreased liver triglyceride level	J:174775
	normal growth/size/body region phenotype	J:174775
	normal homeostasis/metabolism phenotype	J:174775
	hyperglycemia	J:174775
	impaired glucose tolerance	J:174775
	increased circulating insulin level	J:174775
	insulin resistance	J:174775

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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