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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nlrc4
NLR family, CARD domain containing 4
MGI:3036243
6 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Del(13Naip1-Naip5)1Vnce/Del(13Naip1-Naip5)1Vnce
Nlrc4em2Vnce/Nlrc4em2Vnce
involves: C57BL/6 		decreased inflammatory response J:294930
decreased lactate dehydrogenase level J:294930
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Lyz2tm1(cre)Ifo/Lyz2+
Nlrc4tm1Vmd/Nlrc4tm1Vmd
involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NCrl 		normal immune system phenotype J:260047
normal skeleton phenotype J:260047
Nlrc4em1Vnce/Nlrc4em1Vnce
Nlrp3tm1Vmd/Nlrp3tm1Vmd
involves: C57BL/6J * C57BL/6N 		decreased inflammatory response J:294930
decreased lactate dehydrogenase level J:294930
Nlrc4em2Vnce/Nlrc4em2Vnce
Nlrp3tm1Vmd/Nlrp3tm1Vmd
involves: C57BL/6J * C57BL/6N 		decreased inflammatory response J:294930
decreased lactate dehydrogenase level J:294930
Nlrc4tm1Gln/Nlrc4tm1Gln
Slc11a1s/Slc11a1s
B6.129S5-Nlrc4tm1Gln 		increased susceptibility to bacterial infection J:124378
Nlrc4tm1Vmd/Nlrc4tm1Vmd
Nlrp3tm1Vmd/Nlrp3tm1Vmd
C57BL/6-Nlrp3tm1Vmd Nlrc4tm1Vmd 		decreased interleukin-1 beta secretion J:160545
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory