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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
MGI:2673874
14 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
P2ry6tm1.1Brob/P2ry6tm1.1Brob
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal macrophage physiology J:169742
decreased vasoconstriction J:169742
decreased vasodilation J:169742
P2ry6tm1Jabo/P2ry6tm1Jabo
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
B6.Cg-Gt(ROSA)26Sortm9(cre/ESR1)Arte P2ry6tm1Jabo
abnormal respiratory mucosa goblet cell morphology J:179177
increased eosinophil cell number J:179177
increased interferon-gamma secretion J:179177
increased interleukin-4 secretion J:179177
increased interleukin-5 secretion J:179177
increased interleukin-13 secretion J:179177
increased neutrophil cell number J:179177
lung inflammation J:179177
P2ry6tm1Jabo/P2ry6tm1Jabo
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: 129 * C57BL/6 * C57BL/6NTac
abnormal respiratory mucosa goblet cell morphology J:179177
decreased IgE level J:179177
decreased T cell apoptosis J:179177
increased eosinophil cell number J:179177
increased interferon-gamma secretion J:179177
increased interleukin-4 secretion J:179177
increased interleukin-5 secretion J:179177
increased interleukin-13 secretion J:179177
increased neutrophil cell number J:179177
increased T cell proliferation J:179177
lung inflammation J:179177

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory