P2rx2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

P2rx2
purinergic receptor P2X, ligand-gated ion channel, 2
MGI:2665170

19 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
P2rx2^em1(IMPC)H/P2rx2^em1(IMPC)H C57BL/6NTac-P2rx2^em1(IMPC)H/H	decreased circulating glucose level	J:211773
	decreased locomotor activity	J:211773
P2rx2^em1Xzl/P2rx2⁺ CBA/J-P2rx2^em1Xzl	abnormal cochlear inner hair cell morphology	J:315007
	abnormal inner hair cell synaptic ribbon morphology	J:315007
	abnormal nucleotide metabolism	J:315007
	normal behavior/neurological phenotype	J:315007
	normal cellular phenotype	J:315007
	decreased dermal fibroblast proliferation	J:315007
	decreased thermal nociceptive threshold	J:315007
	normal growth/size/body region phenotype	J:315007
	normal hearing/vestibular/ear phenotype	J:315007
	impaired coordination	J:315007
	increased or absent threshold for auditory brainstem response	J:315007
	normal integument phenotype	J:315007
P2rx2^{tm1b(EUCOMM)Hmgu}/P2rx2^{tm1b(EUCOMM)Hmgu} C57BL/6N-P2rx2^{tm1b(EUCOMM)Hmgu}/Ieg	decreased exploration in new environment	J:211773
	small testis	J:211773
P2rx2^tm1Ckn/P2rx2^tm1Ckn involves: 129P2/OlaHsd * C57BL/6	abnormal carotid body physiology	J:86890
	decreased pulmonary ventilation	J:86890
	normal homeostasis/metabolism phenotype	J:86890

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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