Dmrta2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dmrta2
doublesex and mab-3 related transcription factor like family A2
MGI:2653629

26 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dmrta2^tm1.1Fuma/Dmrta2^tm1.1Fuma Tg(Nes-cre)1Kag/0 involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * SJL	normal nervous system phenotype	J:203109
	telencephalon hypoplasia	J:203109
Dmrta2^tm1.2Fuma/Dmrta2^tm1.2Fuma involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * FVB/N * SJL	abnormal cerebral cortex morphology	J:203109
	abnormal neuronal precursor proliferation	J:203109
	absent hippocampus	J:203109
	decreased neuron number	J:203109
	decreased neuronal precursor cell number	J:203109
	normal nervous system phenotype	J:203109
	small olfactory bulb	J:203109
	telencephalon hypoplasia	J:203109
Dmrta2^tm1Ejbd/Dmrta2^tm1Ejbd involves: C57BL/6	abnormal brain commissure morphology	J:215514
	abnormal cerebral cortex morphology	J:215514
	abnormal cerebral hemisphere morphology	J:215514
	abnormal cortical ventricular zone morphology	J:215514
	abnormal hippocampus morphology	J:215514
	abnormal neocortex morphology	J:215514
	abnormal nervous system tract morphology	J:215514
	abnormal neuronal precursor proliferation	J:215514
	abnormal subplate morphology	J:215514
	abnormal telencephalon morphology	J:215514
	absent choroid plexus	J:215514
	absent dentate gyrus	J:215514
	absent gastric milk in neonates	J:215514
	absent hippocampus	J:215514
	decreased body size	J:215514
	decreased Cajal-Retzius cell number	J:215514
	limb grasping	J:215514
	neonatal lethality, incomplete penetrance	J:215514
	normal nervous system phenotype	J:215514
	postnatal growth retardation	J:215514
	small olfactory bulb	J:215514
	thickened cerebral cortex	J:215514
	thin cerebral cortex	J:215514

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23