Dmrta2tm1.2Fuma
Targeted Allele Detail
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Symbol: |
Dmrta2tm1.2Fuma |
Name: |
doublesex and mab-3 related transcription factor like family A2; targeted mutation 1.2, Fumio Matsuzaki |
MGI ID: |
MGI:5527461 |
Gene: |
Dmrta2 Location: Chr4:109835250-109840884 bp, + strand Genetic Position: Chr4, 51.37 cM
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Alliance: |
Dmrta2tm1.2Fuma page
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Reduced cortical size of Dmrta2tm1.2Fuma/Dmrta2tm1.2Fuma newborn brains
Show the 5 phenotype image(s) involving this allele.
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed exon 2.
(J:203109)
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Generation of the Dmrta2tm1.1Fuma and Dmrta2tm1.2Fuma alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dmrta2 Mutation: |
15 strains or lines available
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Original: |
J:203109 Konno D, et al., The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex. PLoS One. 2012;7(10):e46577 |
All: |
2 reference(s) |
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