Dnd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnd1
DND microRNA-mediated repression inhibitor 1
MGI:2447763

24 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnd1^em1(IMPC)Bay/Dnd1^em1(IMPC)Bay C57BL/6N-Dnd1^em1(IMPC)Bay/Bay	abnormal retina outer nuclear layer morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased grip strength	J:211773
	decreased lean body mass	J:211773
	female infertility	J:211773
	increased heart left ventricle size	J:211773
	increased total body fat amount	J:211773
	male infertility	J:211773
Dnd1^Ter/? 129S1/Sv-Kit^W Oca2^p Tyr^c-ch	increased testicular teratoma incidence	J:29502
Dnd1^Ter/Dnd1⁺ 129S1/Sv-Kit^W Oca2^p Tyr^c-ch	increased testicular teratoma incidence	J:7954
Dnd1^Ter/Dnd1⁺ involves: 129P3/J	increased testis tumor incidence	J:221231
Dnd1^Ter/Dnd1⁺ involves: 129S1/Sv * C57BL/6	decreased germ cell number	J:7954
	increased testicular teratoma incidence	J:7954
	increased testis tumor incidence	J:7954
	small ovary	J:7954
	small testis	J:7954
Dnd1^Ter/Dnd1^Ter 129S1/Sv-Kit^W Oca2^p Tyr^c-ch	abnormal ovary morphology	J:7954
	decreased male germ cell number	J:7954
	decreased oocyte number	J:7954
	decreased ovary weight	J:7954
	decreased testis weight	J:7954
	increased testicular teratoma incidence	J:7954
	male infertility	J:7954
	small ovary	J:7954
	small testis	J:7954
Dnd1^Ter/Dnd1^Ter involves: 129S1/Sv * C57BL/6	increased testicular teratoma incidence	J:7954
Dnd1^tm1Na/Dnd1⁺ 129S1.129S6-Dnd1^tm1Na	embryonic lethality, incomplete penetrance	J:221231
	lethality, incomplete penetrance	J:221231
	normal neoplasm	J:221231
	normal reproductive system phenotype	J:221231
Dnd1^tm1Na/Dnd1^Ter involves: 129P3/J * 129S6/SvEvTac	decreased male germ cell number	J:221231
	decreased testis weight	J:221231
	lethality, incomplete penetrance	J:221231

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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