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Dnd1tm1Na
Targeted Allele Detail
Summary
Symbol: Dnd1tm1Na
Name: DND microRNA-mediated repression inhibitor 1; targeted mutation 1, Joseph H Nadeau
MGI ID: MGI:5644313
Synonyms: Dnd1KO
Gene: Dnd1  Location: Chr18:36896724-36899267 bp, - strand  Genetic Position: Chr18, 19.46 cM
Alliance: Dnd1tm1Na page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:221231
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced exon 1, 2 and part of exon 3. (J:221231)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnd1 Mutation:  16 strains or lines available
References
Original:  J:221231 Zechel JL, et al., Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis. BMC Genet. 2013;14:54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory