About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Flnb
filamin, beta
MGI:2446089
85 phenotypes from 6 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
FlnbGt(BGB085)Byg/FlnbGt(BGB085)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal angiogenesis J:120066
abnormal artery development J:120066
abnormal brain vasculature morphology J:120066
abnormal cell physiology J:120066
abnormal hyaline cartilage morphology J:120066
abnormal middle cerebral artery morphology J:120066
abnormal motor capabilities/coordination/movement J:120066
abnormal posture J:120066
abnormal vertebral column morphology J:120066
absent intervertebral disk J:120066
decreased body weight J:120066
decreased bone mineral density J:120066
decreased compact bone thickness J:120066
decreased fibroblast cell migration J:120066
embryonic lethality during organogenesis, incomplete penetrance J:120066
kyphoscoliosis J:120066
perinatal lethality, incomplete penetrance J:120066
premature death J:120066
short tibia J:120066
vertebral fusion J:120066
FlnbGt(RRF239)Byg/FlnbGt(RRF239)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal radius morphology J:132026
abnormal sternum morphology J:132026
abnormal ulna morphology J:132026
decreased body size J:132026
decreased body weight J:132026
fused carpal bones J:132026
neonatal lethality, incomplete penetrance J:132026
postnatal lethality, incomplete penetrance J:132026
scoliosis J:132026
vertebral fusion J:132026
FlnbGt(XD076)Byg/FlnbGt(XD076)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal bone mineralization J:134094
abnormal bone ossification J:134094
abnormal chondrocyte morphology J:134094
abnormal posture J:134094
abnormal sternebra morphology J:134094
cervical vertebral fusion J:134094
decreased body size J:134094
decreased survivor rate J:134094
fused carpal bones J:134094
kyphosis J:134094
postnatal lethality, incomplete penetrance J:134094
Flnbskm2/Flnbskm2
involves: 129S1/SvImJ * 129X1/SvJ * DBA/2J
abnormal gait J:218364
abnormal sternum morphology J:218364
abnormal thoracic cage morphology J:218364
decreased body height J:218364
decreased rib number J:218364
dehydration J:218364
lordosis J:218364
preweaning lethality, incomplete penetrance J:218364
scoliosis J:218364
tachypnea J:218364
thoracic vertebral fusion J:218364
Flnbtm1b(KOMP)Wtsi/Flnb+
C57BL/6N-Flnbtm1b(KOMP)Wtsi/H
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased lean body mass J:211773
decreased neutrophil cell number J:211773
decreased red blood cell distribution width J:211773
increased circulating serum albumin level J:211773
increased total body fat amount J:211773
Flnbtm1b(KOMP)Wtsi/Flnbtm1b(KOMP)Wtsi
C57BL/6N-Flnbtm1b(KOMP)Wtsi/H
preweaning lethality, complete penetrance J:211773
Flnbtm1Vshn/Flnbtm1Vshn
involves: 129S6/SvEvTac * C57BL/6
abnormal cell adhesion J:125095
abnormal chondrocyte morphology J:125095, J:213355
abnormal chondrocyte physiology J:125095, J:213355
abnormal extracellular matrix morphology J:125095
abnormal limb bone morphology J:125095
abnormal long bone epiphyseal plate morphology J:213355
abnormal long bone epiphyseal plate proliferative zone J:125095, J:213355
abnormal neurocranium morphology J:125095
abnormal occipital bone morphology J:125095
abnormal parietal bone morphology J:125095
abnormal patella morphology J:125095
abnormal perichondrium morphology J:125095
abnormal radius morphology J:125095
abnormal skeleton development J:125095
abnormal thoracic cage morphology J:125095
abnormal ulna morphology J:125095
abnormal viscerocranium morphology J:125095
brachyphalangia J:125095
cervical vertebral fusion J:125095
decreased bone mineral density J:125095
decreased bone mineral density of vertebrae J:125095
decreased bone mineralization J:125095
decreased bone ossification J:125095
decreased diameter of radius J:125095
decreased diameter of ulna J:125095
decreased distal limb length J:125095
decreased length of long bones J:213355
decreased long bone epiphyseal plate size J:125095, J:213355
decreased width of hypertrophic chondrocyte zone J:125095
delayed bone ossification J:125095
delayed endochondral bone ossification J:125095
delayed intramembranous bone ossification J:125095
increased width of hypertrophic chondrocyte zone J:213355
joint laxity J:125095
kyphosis J:125095
lordosis J:125095
postnatal growth retardation J:125095
preweaning lethality, incomplete penetrance J:125095
rib fusion J:125095
scoliosis J:125095
short radius J:125095, J:213355
slow postnatal weight gain J:125095
small thoracic cage J:125095
thin ribs J:125095
vertebral fusion J:125095

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory