About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
MGI:2442345
33 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Hif1antm1.1Rsjo/Hif1antm1.1Rsjo
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129 * C57BL/6 * DBA
no abnormal phenotype detected J:160941
Hif1antm1.1Rsjo/Hif1antm1.1Rsjo
Tg(Nes-cre)1Wme/0
involves: 129 * C57BL/6 * CBA
decreased circulating insulin level J:160941
decreased susceptibility to weight gain J:160941
increased insulin sensitivity J:160941
Hif1antm1.2Rsjo/Hif1antm1.2Rsjo
B6.129-Hif1antm1.2Rsjo
abnormal cell physiology J:160941
abnormal circulating hormone level J:160941
abnormal lung volume J:160941
abnormal oxygen level J:160941
alkalosis J:160941
decreased body weight J:160941
decreased circulating cholesterol level J:160941
decreased circulating glucose level J:160941
decreased circulating HDL cholesterol level J:160941
decreased circulating insulin level J:160941
decreased circulating LDL cholesterol level J:160941
decreased circulating triglyceride level J:160941
decreased circulating VLDL triglyceride level J:160941
decreased epididymal fat pad weight J:160941
decreased liver triglyceride level J:160941
decreased liver weight J:160941
decreased quadriceps weight J:160941
decreased susceptibility to hepatic steatosis J:160941
decreased susceptibility to weight gain J:160941
decreased white fat cell size J:160941
hypoactivity J:160941
hypocapnia J:160941
increased basal metabolism J:160941
increased carbon dioxide production J:160941
increased circulating cholesterol level J:160941
increased fluid intake J:160941
increased food intake J:160941
increased heart rate J:160941
increased insulin sensitivity J:160941
increased oxygen consumption J:160941
increased pulmonary respiratory rate J:160941
increased tidal volume J:160941

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/05/2019
MGI 6.14
The Jackson Laboratory