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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gjc2
gap junction protein, gamma 2
MGI:2153060
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gjb1tm1Kwi/Y
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal gait J:219594
abnormal oligodendrocyte apoptosis J:219594
abnormal oligodendrocyte morphology J:219594
astrocytosis J:219594
axon degeneration J:219594
demyelination J:219594
dysmyelination J:219594
impaired coordination J:219594
microgliosis J:219594
optic nerve inflammation J:219594
premature death J:219594
spinal cord inflammation J:219594
tonic seizures J:219594
tremors J:219594
Gjb1tm1Kwi/Y
Gjc2tm2.1Kwi/Gjc2tm2.1Kwi
involves: 129S4/SvJae * C57BL/6 * SJL 		abnormal motor capabilities/coordination/movement J:174197
abnormal myelination J:174197
astrocytosis J:174197
ataxia J:174197
premature death J:174197
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi
Gjb1tm1Kwi/Gjb1tm1Kwi
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal gait J:219594
abnormal myelination J:83885
abnormal oligodendrocyte apoptosis J:219594
abnormal oligodendrocyte morphology J:219594
astrocytosis J:219594
axon degeneration J:219594
demyelination J:219594
dysmyelination J:219594
impaired coordination J:219594
microgliosis J:219594
neurodegeneration J:83885
optic nerve inflammation J:219594
premature death J:83885, J:219594
seizures J:83885
spinal cord inflammation J:219594
sporadic seizures J:83885
tonic seizures J:83885, J:219594
tremors J:83885, J:219594
Gjc2tm1Paul/Gjc2tm1Paul
Gjb1tm1Kwi/Gjb1tm1Kwi
involves: 129/Sv * C57BL/6 		abnormal myelination J:84338
absent optic nerve J:84338
demyelination J:84338
premature death J:84338
tonic seizures J:84338
tremors J:84338
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory