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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Jam3
junction adhesion molecule 3
MGI:1933825
48 phenotypes from 5 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Jam3tm1.1(KOMP)Vlcg/Jam3tm1.1(KOMP)Vlcg
C57BL/6N-Jam3tm1.1(KOMP)Vlcg/J
male infertility J:211773
preweaning lethality, incomplete penetrance J:211773
Jam3tm1.1Chav/Jam3tm1.1Chav
Tg(Tal1-cre/ERT)1Jrg/?
involves: 129 * C57BL/6
decreased metastatic potential J:173391
Jam3tm1.1Chav/Jam3tm1.2Chav
Tg(Cdh5-cre)7Mlia/?
involves: 129 * C57BL/6 * FVB/N
decreased metastatic potential J:173391
Jam3tm1.2Chav/Jam3tm1.2Chav
B6.129-Jam3tm1.2Chav
decreased metastatic potential J:173391
male infertility J:173391
prenatal lethality, incomplete penetrance J:173391
preweaning lethality, incomplete penetrance J:173391
Jam3tm1.2Chav/Jam3tm1.2Chav
involves: 129 * C57BL/6
male infertility J:173391
prenatal lethality, incomplete penetrance J:173391
preweaning lethality, incomplete penetrance J:173391
Jam3tm1Rha/Jam3tm1.1Chav
Tg(Spo11-cre)D5Mpel/0
involves: 129P2/OlaHsd * BALB/c * C57BL/6
abnormal male germ cell apoptosis J:166888
abnormal manchette morphology J:166888
abnormal spermatid morphology J:166888
arrest of spermatogenesis J:166888
decreased male germ cell number J:166888
small testis J:166888
Jam3tm1Rha/Jam3tm1Rha
B6.129P2-Jam3tm1Rha
abnormal cerebral cortex morphology J:191990
abnormal cerebral cortex pyramidal cell morphology J:191990
abnormal cranium morphology J:191990
abnormal gait J:191990
abnormal hippocampus morphology J:191990
abnormal innervation J:191990
abnormal nervous system physiology J:191990
cerebellum atrophy J:191990
dilated lateral ventricles J:191990
disheveled coat J:191990
enlarged cranium J:191990
gliosis J:191990
hydrocephaly J:191990
internal hemorrhage J:191990
intracranial hemorrhage J:191990
intraventricular hemorrhage J:191990
lethargy J:191990
obstructive hydrocephaly J:191990
postnatal growth retardation J:191990
postnatal lethality, incomplete penetrance J:191990
thin cerebral cortex J:191990
tremors J:191990
Jam3tm1Rha/Jam3tm1Rha
involves: 129P2/OlaHsd * C57BL/6
abnormal digestive system physiology J:121841
abnormal respiratory system physiology J:121841
abnormal seminiferous tubule morphology J:92665
arrest of spermatogenesis J:92665
enlarged esophagus J:121841
globozoospermia J:92665
increased granulocyte number J:121841
increased susceptibility to bacterial infection J:121841
lung inflammation J:121841
male infertility J:92665, J:121841
postnatal lethality J:92665
postnatal lethality, incomplete penetrance J:121841
small testis J:92665
Jam3tm1Rha/Jam3tm1Rha
Tg(Tek-Jam3)1Maal/0
B6.Cg-Jam3tm1Rha Tg(Tek-Jam3)1Maal
hydrocephaly J:191990
postnatal lethality, incomplete penetrance J:191990
Jam3tm1Rha/Jam3tm1Rha
Tg(Tek-Jam3)1Maal/?
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA
enlarged esophagus J:121841
normal immune system phenotype J:121841
male infertility J:121841
normal mortality/aging J:121841
Tg(Tek-Jam3)1Maal/?
B6.Cg-Tg(Tek-Jam3)1Maal
abnormal cellular extravasation J:99020
abnormal leukocyte adhesion J:99020
abnormal leukocyte physiology J:99020
impaired neutrophil chemotaxis J:99020
lung inflammation J:99020
peritoneal inflammation J:99020

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory