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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tlr9
toll-like receptor 9
MGI:1932389
27 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Faslpr/Faslpr
Tlr9tm1Aki/Tlr9tm1Aki
B6.Cg-Tlr9tm1Aki Faslpr
autoimmune response J:135036
decreased IgM level J:135036
enlarged lymph nodes J:135036
enlarged spleen J:135036
glomerulonephritis J:135036
increased double-negative T cell number J:135036
increased IgG level J:135036
increased urine protein level J:135036
premature death J:135036
renal glomerular immunoglobulin deposits J:135036
Faslpr/Faslpr
Tlr9tm1Aki/Tlr9tm1Aki
MRL.Cg-Tlr9tm1Aki Faslpr
abnormal B cell activation J:113557
abnormal plasmacytoid dendritic cell physiology J:113557
abnormal renal glomerulus morphology J:113557
decreased autoantibody level J:113557
enlarged lymph nodes J:113557
enlarged spleen J:113557
glomerulonephritis J:113557
increased autoantibody level J:113557
increased CD4-positive, alpha-beta T cell number J:113557
increased circulating interferon-alpha level J:113557
increased double-negative T cell number J:113557
increased IgG2a level J:113557
increased IgG3 level J:113557
increased IgG level J:113557
increased susceptibility to systemic lupus erythematosus J:113557
kidney inflammation J:113557
premature death J:113557
Pld4tm1.2Nemz/Pld4tm1.2Nemz
Tlr9M7Btlr/Tlr9M7Btlr
involves: 129 * C57BL/6J * FVB/N
normal hematopoietic system phenotype J:281205
normal homeostasis/metabolism phenotype J:281205
normal immune system phenotype J:281205
Smcr8em1Btlr/Smcr8em1Btlr
Tlr3tm1Flv/Tlr3tm1Flv
Tlr7tm1Aki/Tlr7tm1Aki
Tlr9tm1Aki/Tlr9tm1Aki
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6J
normal immune system phenotype J:268243
Tlr9tm1Aki/Tlr9tm1Aki
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0
involves: 129P2/OlaHsd * C57BL/6
decreased mature B cell number J:115059
increased B-1 B cell number J:115059
Tlr9tm1Aki/Tlr9tm1Aki
Unc93b1tm1.1Kmiy/Unc93b1tm1.1Kmiy
involves: 129P2/OlaHsd * C57BL/6
premature death J:174308
thrombocytopenia J:174308

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory