Cldn12 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cldn12
claudin 12
MGI:1929288

41 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cldn12^{tm1.1(KOMP)Vlcg}/Cldn12^{tm1.1(KOMP)Vlcg} B6J.B6N-Cldn12^{tm1.1(KOMP)Vlcg}	abnormal circulating non-HDL cholesterol level	J:279934
	abnormal heart echocardiography feature	J:279934
	abnormal motor coordination/balance	J:279934
	decreased anxiety-related response	J:279934
	decreased body length	J:279934
	decreased body mass index	J:279934
	decreased bone mineral content	J:279934
	decreased bone volume	J:279934
	decreased cardiac stroke volume	J:279934
	decreased circulating free fatty acids level	J:279934
	decreased circulating total protein level	J:279934
	decreased circulating triglyceride level	J:279934
	decreased erythrocyte cell number	J:279934
	decreased fasting circulating glucose level	J:279934
	decreased food intake	J:279934
	decreased locomotor activity	J:279934
	decreased respiratory quotient	J:279934
	decreased startle reflex	J:279934
	decreased total retina thickness	J:279934
	decreased vertical activity	J:279934
	normal immune system phenotype	J:279934
	increased alkaline phosphatase activity	J:279934
	increased body fat mass	J:279934
	increased body weight	J:279934
	increased cardiac muscle contractility	J:279934
	increased circulating creatinine level	J:279934
	increased circulating glucose level	J:279934
	increased leukocyte cell number	J:279934
	increased liver weight	J:279934
	increased mean corpuscular hemoglobin	J:279934
	increased or absent threshold for auditory brainstem response	J:279934
	increased spleen weight	J:279934
	macrocytosis	J:279934
	microphthalmia	J:279934
	normal nervous system phenotype	J:279934
	preweaning lethality, incomplete penetrance	J:279934
	shortened PQ interval	J:279934
	shortened PR interval	J:279934
	tremors	J:279934
Cldn12^{tm1b(EUCOMM)Wtsi}/Cldn12^{tm1b(EUCOMM)Wtsi} C57BL/6N-Cldn12^{tm1b(EUCOMM)Wtsi}/Bay	hyperactivity	J:211773
	increased grip strength	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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