Ccdc88a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccdc88a
coiled coil domain containing 88A
MGI:1925177

36 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccdc88a^tm1Mat/Ccdc88a⁺ Not Specified	abnormal excitatory postsynaptic currents	J:217412
	abnormal long-term object recognition memory	J:217412
	impaired contextual conditioning behavior	J:217412
	impaired spatial learning	J:217412
	reduced long-term potentiation	J:217412
Ccdc88a^tm1Mat/Ccdc88a^tm1Mat Not Specified	abnormal GABAergic neuron morphology	J:173379
	abnormal neocortex morphology	J:173379
	abnormal neuron differentiation	J:173379
	abnormal neuronal precursor cell migration	J:173379
	abnormal olfactory bulb development	J:173379
	abnormal olfactory bulb glomerular layer morphology	J:173379
	abnormal olfactory bulb granule cell layer morphology	J:173379
	abnormal olfactory bulb mitral cell layer morphology	J:173379
	abnormal olfactory bulb morphology	J:173379
	abnormal olfactory bulb subventricular zone morphology	J:173379
	abnormal retina vasculature morphology	J:145672
	abnormal rostral migratory stream morphology	J:173379
	decreased angiogenesis	J:145672
	decreased body weight	J:145672
	decreased brain size	J:173379
	decreased neuron number	J:173379
	normal nervous system phenotype	J:173379
	premature death	J:145672
	small olfactory bulb	J:173379
	weight loss	J:145672
Ccdc88a^tm2.1Mat/Ccdc88a^tm2.1Mat involves: 129S6/SvEvTac * C57BL/6	abnormal dendritic spine morphology	J:217412
	abnormal excitatory postsynaptic currents	J:217412
	abnormal habituation to a new environment	J:217412
	decreased prepulse inhibition	J:217412
	normal growth/size/body region phenotype	J:173379
	impaired contextual conditioning behavior	J:217412
	impaired long-term object recognition memory	J:217412
	impaired spatial learning	J:217412
	normal mortality/aging	J:173379
	reduced long-term potentiation	J:217412
	reduced sensorimotor gating	J:217412
Ccdc88a^tm3.1Mat/Ccdc88a^tm3.1Mat involves: 129S6/SvEvTac * C57BL/6	abnormal neuronal precursor cell migration	J:173379
	abnormal olfactory bulb development	J:173379
	abnormal rostral migratory stream morphology	J:173379
	premature death	J:173379
	weight loss	J:173379
Ccdc88a^tm4.1Mat/Ccdc88a⁺ Tg(Nes-cre)1Kln/0 involves: 129 * C57BL/6 * SJL	small olfactory bulb	J:190129
Ccdc88a^tm4.1Mat/Ccdc88a^tm4.1Mat Tg(Nes-cre)1Kln/0 involves: 129 * C57BL/6 * SJL	abnormal dentate gyrus morphology	J:190129
	abnormal rostral migratory stream morphology	J:190129
	decreased body weight	J:190129
	decreased locomotor activity	J:190129
	postnatal growth retardation	J:190129
	postnatal lethality, complete penetrance	J:190129
	small olfactory bulb	J:190129

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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