Dnase1l2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnase1l2
deoxyribonuclease 1-like 2
MGI:1913955

49 phenotypes from 6 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnase1l2^em1(IMPC)Bay/Dnase1l2^em1(IMPC)Bay C57BL/6N-Dnase1l2^em1(IMPC)Bay/Bay	abnormal spleen morphology	J:211773
	decreased bone mineral density	J:211773
Dnase1l2^em1(IMPC)J/Dnase1l2^em1(IMPC)J C57BL/6NJ-Dnase1l2^em1(IMPC)J/J	hyperactivity	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
Dnase1l2^em2(IMPC)Mbp/Dnase1l2^em2(IMPC)Mbp C57BL/6N-Dnase1l2^em2(IMPC)Mbp/Ucd	abnormal heart morphology	J:211773
	enlarged heart	J:211773
	hydrometra	J:211773
	small superior vagus ganglion	J:211773
Dnase1l2^{tm1(KOMP)Wtsi}/Dnase1l2^{tm1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1(KOMP)Wtsi}/Wtsi	abnormal autopod morphology	J:211773
	abnormal bone structure	J:211773
	abnormal digit morphology	J:211773
	abnormal tail length	J:211773
	abnormal tail morphology	J:211773
	brachydactyly	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	increased heart weight	J:211773
	increased total body fat amount	J:211773
	short tibia	J:211773
Dnase1l2^{tm1(KOMP)Wtsi}/Dnase1l2^{tm1(KOMP)Wtsi} involves: C57BL/6N	decreased grip strength	J:200082
	fused joints	J:200082
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2⁺ C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/Bay	abnormal stomach morphology	J:211773
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/Bay	abnormal heart left ventricle morphology	J:211773
	abnormal joint morphology	J:211773
	abnormal maxilla morphology	J:211773
	abnormal spleen morphology	J:211773
	brachydactyly	J:211773
	decreased cardiac stroke volume	J:211773
	decreased grip strength	J:211773
	short tibia	J:211773
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/H	abnormal bone structure	J:211773
	abnormal digit morphology	J:211773
	abnormal joint morphology	J:211773
	abnormal tail morphology	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	decreased total body fat amount	J:211773
	increased blood urea nitrogen level	J:211773
	persistence of hyaloid vascular system	J:211773
	short tibia	J:211773
	vertebral fusion	J:211773
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/Ieg	abnormal autopod morphology	J:211773
	abnormal digit morphology	J:211773
	abnormal lens morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal vocalization	J:211773
	decreased body length	J:211773
	decreased locomotor activity	J:211773
	increased blood urea nitrogen level	J:211773
	increased fasting circulating glucose level	J:211773
	short tibia	J:211773
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/J	decreased body length	J:211773
	increased fasting circulating glucose level	J:211773
	increased heart weight	J:211773
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/Orl	abnormal digit morphology	J:211773
	abnormal head morphology	J:211773
	abnormal motor capabilities/coordination/movement	J:211773
	abnormal nail morphology	J:211773
	abnormal tail morphology	J:211773
	decreased body length	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	increased circulating calcium level	J:211773
	persistence of hyaloid vascular system	J:211773
	short tibia	J:211773
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/Ucd	abnormal bone structure	J:211773
	abnormal cranium morphology	J:211773
	abnormal digit morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal optic disk morphology	J:211773
	brachydactyly	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased grip strength	J:211773
	decreased total body fat amount	J:211773
	short tibia	J:211773
Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi} C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/Wtsi	abnormal bone structure	J:211773
	abnormal digit morphology	J:211773
	abnormal joint morphology	J:211773
	abnormal spine curvature	J:211773
	abnormal tail morphology	J:211773
	abnormal tibia morphology	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased grip strength	J:211773
	decreased lean body mass	J:211773
	decreased total body fat amount	J:211773
	eye hemorrhage	J:211773
	fusion of vertebral arches	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased total body fat amount	J:211773
	short tibia	J:211773
Dnase1l2^tm1Eckh/Dnase1l2^tm1Eckh involves: 129S6/SvEvTac	abnormal cell nucleus morphology	J:180935
	abnormal hair shaft morphology	J:180935
	abnormal nail morphology	J:180935

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