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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Zfp423
zinc finger protein 423
MGI:1891217
53 phenotypes from 7 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Zfp423Gt(pT1Betageo)1Ruiz/Zfp423Gt(pT1Betageo)1Ruiz
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:85162
Zfp423Gt(XB409)Byg/Zfp423Gt(XB409)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal cerebellar plate morphology J:122606
abnormal forebrain morphology J:122606
abnormal interventricular foramen morphology J:122606
abnormal medulla oblongata morphology J:122606
ataxia J:122606
decreased body size J:122606
enlarged fourth ventricle J:122606
enlarged lateral ventricles J:122606
neonatal lethality, incomplete penetrance J:122275, J:122606
postnatal lethality, complete penetrance J:122606
Zfp423Gt(XH542)Byg/Zfp423Gt(XH542)Byg
involves: 129P2/OlaHsd * C57BL/6
normal behavior/neurological phenotype J:111316
Zfp423Gt(XH542)Byg/Zfp423tm1.2Ngc
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CD-1
reduced cerebellar foliation J:111316
small cerebellum J:111316
Zfp423nur12/Zfp423Gt(XH542)Byg
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C3H
abnormal gait J:114758
cerebellum hypoplasia J:114758
Zfp423nur12/Zfp423nur12
involves: BALB/c * C57BL/6 * C3H
abnormal cerebellar cortex morphology J:114758
abnormal cerebellum morphology J:114758
abnormal choroid plexus morphology J:114758
abnormal hippocampus morphology J:114758
abnormal telencephalon morphology J:114758
absent corpus callosum J:114758
ataxia J:114758
cerebellum vermis hypoplasia J:114758
decreased body weight J:114758
dilated fourth ventricle J:114758
dilated lateral ventricles J:114758
tremors J:114758
Zfp423nur12/Zfp423nur12
Not Specified
ataxia J:85113
lethality at weaning, complete penetrance J:85113
tremors J:85113
Zfp423tm1.1Ngc/Zfp423tm1.1Ngc
involves: 129S1/Sv * C57BL/6 * CD-1
no abnormal phenotype detected J:111316
Zfp423tm1.2Ngc/Zfp423tm1.2Ngc
involves: 129S1/Sv * C57BL/6 * CD-1
abnormal cerebellum morphology J:111316
abnormal cerebellum vermis morphology J:111316
abnormal food intake J:111316
abnormal gait J:111316
abnormal motor coordination/balance J:111316
abnormal Purkinje cell dendrite morphology J:111316
ataxia J:111316
decreased body size J:111316
decreased brain size J:111316
decreased hindbrain size J:111316
dehydration J:111316
ectopic Purkinje cell J:111316
lethality at weaning, incomplete penetrance J:111316
premature death J:111316
reduced cerebellar foliation J:111316
Zfp423tm1Reed/Zfp423tm1Reed
involves: 129 * C57BL/6
abnormal cerebellar cortex morphology J:122606
abnormal cerebellar granule cell precursor proliferation J:122606
abnormal cerebellum development J:122606
abnormal cerebellum lateral hemisphere morphology J:122606
abnormal corpus callosum morphology J:122606
abnormal forebrain morphology J:122606
abnormal hippocampal commissure morphology J:122606
abnormal Purkinje cell dendrite morphology J:122606
absent cerebellum J:122606
absent cerebellum vermis J:122606
ataxia J:122606
cerebellum vermis hypoplasia J:122606
decreased body weight J:122606
decreased Purkinje cell number J:122606
enlarged lateral ventricles J:122606
postnatal lethality, incomplete penetrance J:122606
premature death J:122606
reduced cerebellar foliation J:122606
small thalamus J:122606
Zfp423tm1Reed/Zfp423tm1Reed
Not Specified
abnormal cerebellum morphology J:122275
abnormal nasal cavity morphology J:122275
abnormal olfactory bulb morphology J:122275
abnormal olfactory epithelium morphology J:122275
abnormal olfactory nerve morphology J:122275
ataxia J:122275
decreased body size J:122275
lethality at weaning, complete penetrance J:122275
small olfactory bulb J:122275

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory