Il27ra Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il27ra
interleukin 27 receptor, alpha
MGI:1355318

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fas^lpr/Fas^lpr Il27ra^tm1Mak/Il27ra^tm1Mak MRL.Cg-Il27ra^tm1Mak Fas^lpr	abnormal T-helper 2 physiology	J:122148
	decreased anti-double stranded DNA antibody level	J:122148
	decreased blood urea nitrogen level	J:122148
	decreased circulating creatinine level	J:122148
	decreased IgG2a level	J:122148
	decreased interferon-gamma secretion	J:122148
	decreased susceptibility to systemic lupus erythematosus	J:122148
	extended life span	J:122148
	glomerulonephritis	J:122148
	normal immune system phenotype	J:122148
	increased circulating interleukin-4 level	J:122148
	increased circulating interleukin-5 level	J:122148
	increased IgE level	J:122148
	increased IgG1 level	J:122148
Il10^tm1Cgn/Il10^tm1Cgn Il27ra^tm1Mak/Il27ra^tm1Mak involves: 129P2/OlaHsd * C57BL/6	abnormal T-helper 1 physiology	J:136179
	abnormal T-helper 2 physiology	J:136179
	colitis	J:136179
	decreased interferon-gamma secretion	J:136179
	decreased susceptibility to induced colitis	J:136179
	extended life span	J:136179
	increased interleukin-13 secretion	J:136179

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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