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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tnfsf14
tumor necrosis factor (ligand) superfamily, member 14
MGI:1355317
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd28tm1Mak/Cd28tm1Mak
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		increased length of allograft survival J:77250
Ltatm1Dch/Ltatm1Dch
Tnfsf14tm1Lpc/Tnfsf14tm1Lpc
involves: 129S2/SvPas * 129X1/SvJ 		abnormal lymphocyte morphology J:173115
abnormal thymus epithelium morphology J:173115
small thymus medulla J:173115
Ltbtm1Kpf/Ltbtm1Kpf
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
involves: 129P2/OlaHsd * C57BL/6 		abnormal mesenteric lymph node morphology J:77250
abnormal spleen morphology J:77250
absent axillary lymph nodes J:77250
absent brachial lymph nodes J:77250
absent inguinal lymph nodes J:77250
absent lymph nodes J:77250
absent Peyer's patches J:77250
absent popliteal lymph nodes J:77250
Ltbrtm1Kpf/Ltbrtm1Kpf
Tg(Lck-Tnfsf14)24Yxf/?
B6.Cg-Ltbrtm1Kpf Tg(Lck-Tnfsf14)24Yxf 		normal digestive/alimentary phenotype J:128976
normal homeostasis/metabolism phenotype J:120962
normal immune system phenotype J:128976
Rag1tm1Mom/Rag1tm1Mom
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal trabecular bone morphology J:294030
decreased osteoclast cell number J:294030
increased osteoblast cell number J:294030
Tg(Lck-Tnfsf14)24Yxf/?
Tnfrsf14tm1Kpf/Tnfrsf14tm1Kpf
involves: 129P2/OlaHsd * C57BL/6 		increased circulating cholesterol level J:120962
Tg(Tnfsf13b)1Fma/0
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J 		abnormal mesangial cell morphology J:114782
abnormal spleen germinal center morphology J:114782
abnormal spleen marginal zone morphology J:114782
increased B cell number J:114782
increased IgA level J:114782
increased plasma cell number J:114782
renal glomerular immunoglobulin deposits J:114782
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory