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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lats2
large tumor suppressor 2
MGI:1354386
27 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lats2tm1.1Dupa/Lats2tm1.1Dupa
involves: 129P2/OlaHsd
no abnormal phenotype detected J:223215
Lats2tm1.1Jfm/Lats2tm1.1Jfm
involves: 129S6/SvEvTac * C57BL/6Brd * CD-1
no abnormal phenotype detected J:101977
Lats2tm1Dgen/Lats2+
involves: 129P2/OlaHsd * C57BL/6
abnormal startle reflex J:101679
Lats2tm1Dgen/Lats2tm1Dgen
involves: 129P2/OlaHsd * C57BL/6
embryonic lethality during organogenesis, complete penetrance J:101679
Lats2tm1Noj/Lats2+
involves: 129S2/SvPas * C57BL/6
prenatal lethality, complete penetrance J:123480
Lats2tm1Noj/Lats2tm1Noj
involves: 129S2/SvPas
abnormal centrosome morphology J:200232
Lats2tm1Noj/Lats2tm1Noj
involves: 129S2/SvPas * C57BL/6
abnormal cell morphology J:123480
abnormal cell nucleus morphology J:123480
abnormal fourth ventricle morphology J:123480
abnormal mitosis J:123480
abnormal pharyngeal arch morphology J:123480
abnormal spinal cord morphology J:123480
decreased embryo size J:123480
delayed muscle development J:123480
embryonic growth retardation J:123480
embryonic lethality during organogenesis, complete penetrance J:123480
increased cell nucleus count J:123480
increased spinal cord apoptosis J:123480
polyploidy J:123480
small heart J:123480
Lats2tm1Raz/Lats2tm1Raz
involves: 129P2/OlaHsd * C57BL/6
abnormal cell proliferation J:93191
abnormal heart atrium morphology J:93191
chromosome breakage J:93191
decreased cell proliferation J:93191
embryonic growth retardation J:93191
embryonic lethality during organogenesis, complete penetrance J:93191
hemopericardium J:93191
hemorrhage J:93191
trabecula carnea hypoplasia J:93191
ventricular hypoplasia J:93191
wavy neural tube J:93191

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory