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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Casr
calcium-sensing receptor
MGI:1351351
58 phenotypes from 9 alleles in 14 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
CasrBCH002/CasrBCH002
C3HeB/FeJ-CasrBCH002
abnormal coat/hair pigmentation J:183993
decreased body size J:183993
decreased circulating phosphate level J:183993
increased circulating calcium level J:183993
CasrBCH003/CasrBCH003
C3HeB/FeJ-CasrBCH003
increased circulating calcium level J:183993
CasrBCH004/CasrBCH004
C3HeB/FeJ-CasrBCH004
increased circulating calcium level J:183993
CasrBCH007/CasrBCH007
C3HeB/FeJ-CasrBCH007
decreased body size J:183993
increased circulating calcium level J:183993
CasrBCH011/CasrBCH011
C3HeB/FeJ-CasrBCH011
increased circulating calcium level J:183993
CasrBCH013/CasrBCH013
C3HeB/FeJ-CasrBCH013
increased circulating calcium level J:183993
CasrNuf/Casr+
either: (involves: 102/El * 102/H * C3H/He) or (involves: 102/El * C3H/He * C3H/HeH)
cataract J:92612
decreased circulating calcium level J:92612
decreased circulating parathyroid hormone level J:92612
increased circulating phosphate level J:92612
CasrNuf/CasrNuf
involves: 102/El * C3H/He
calcified muscle J:92612
calcinosis J:92612
cataract J:92612
decreased circulating calcium level J:92612
decreased circulating parathyroid hormone level J:92612
decreased urine calcium level J:92612
decreased urine phosphate level J:92612
increased circulating phosphate level J:92612
nephrocalcinosis J:92612
premature death J:92612
tongue inflammation J:92612
Casrtm1Ces/Casr+
involves: 129X1/SvJ * Black Swiss
decreased urine calcium level J:29900
normal endocrine/exocrine gland phenotype J:29900
normal growth/size/body region phenotype J:29900
normal hematopoietic system phenotype J:29900
increased circulating calcium level J:29900
increased circulating magnesium level J:29900
increased circulating parathyroid hormone level J:29900
normal renal/urinary system phenotype J:29900
normal skeleton phenotype J:29900
Casrtm1Ces/Casrtm1Ces
involves: 129X1/SvJ * Black Swiss
abnormal bone mineralization J:71056
abnormal parathyroid gland chief cell morphology J:29900
abnormal postural reflex J:29900
abnormal posture J:29900
aphagia J:29900
decreased body size J:71056
decreased body weight J:71056
decreased bone mineral density J:29900
decreased circulating phosphate level J:71056
decreased urine calcium level J:29900
dehydration J:29900
delayed bone ossification J:71056
enlarged parathyroid gland J:29900
increased circulating calcium level J:29900
increased circulating magnesium level J:29900
increased circulating parathyroid hormone level J:29900
increased hematocrit J:29900
increased width of hypertrophic chondrocyte zone J:71056
kyphoscoliosis J:29900
lethargy J:29900
parathyroid gland hyperplasia J:29900
pigmented parathyroid gland J:29900
postnatal growth retardation J:29900
postnatal lethality, complete penetrance J:29900, J:71056
rickets J:71056
Casrtm1Wch/Casr+
Tg(PTH-cre)4167Slib/0
involves: 129S4/SvJae * C57BL/6 * FVB
decreased bone mineral density J:180651
decreased bone trabecula number J:180651
decreased compact bone thickness J:180651
decreased compact bone volume J:180651
decreased trabecular bone thickness J:180651
increased circulating calcium level J:180651
increased circulating parathyroid hormone level J:180651
increased urine calcium level J:180651
normal skeleton phenotype J:180651
Casrtm1Wch/Casrtm1Wch
Tg(Col1a1-cre)2Bek/0
involves: 129S4/SvJae * C57BL/6 * CD-1
abnormal skeleton development J:180651
abnormal skeleton morphology J:180651
abnormal trabecular bone morphology J:180651
decreased body size J:180651
decreased body weight J:180651
decreased bone mineral density J:180651
decreased bone mineralization J:180651
decreased bone trabecula number J:180651
decreased compact bone thickness J:180651
decreased compact bone volume J:180651
decreased trabecular bone connectivity density J:180651
decreased trabecular bone thickness J:180651
decreased trabecular bone volume J:180651
fragile skeleton J:180651
postnatal growth retardation J:180651
postnatal lethality, complete penetrance J:180651
Casrtm1Wch/Casrtm1Wch
Tg(Col2a1-cre)1Bhr/0
involves: 129S4/SvJae * C57BL/6 * SJL
abnormal skeleton development J:180651
decreased bone mineralization J:180651
embryonic lethality during organogenesis, incomplete penetrance J:180651
lethality throughout fetal growth and development, complete penetrance J:180651
Casrtm1Wch/Casrtm1Wch
Tg(Col2a1-cre/ERT)KA3Smac/0
involves: 129S4/SvJae * C57BL/6 * FVB/N
abnormal skeleton development J:180651
decreased bone mineralization J:180651
increased width of hypertrophic chondrocyte zone J:180651
Casrtm1Wch/Casrtm1Wch
Tg(PTH-cre)4167Slib/0
involves: 129S4/SvJae * C57BL/6 * FVB
abnormal skeleton development J:180651
abnormal skeleton morphology J:180651
decreased body weight J:180651
decreased bone mineral content J:180651
decreased bone mineral density J:180651
decreased bone mineralization J:180651
fragile skeleton J:180651
increased circulating calcium level J:180651
increased circulating parathyroid hormone level J:180651
increased urine calcium level J:180651
postnatal growth retardation J:180651
postnatal lethality, complete penetrance J:180651
Casrtm1Wch/Casrtm1Wch
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S4/SvJae * C57BL/6 * CD-1
abnormal skeleton development J:180651
abnormal trabecular bone morphology J:180651
decreased body size J:180651
decreased bone mineralization J:180651
decreased bone trabecula number J:180651
decreased compact bone volume J:180651
decreased trabecular bone connectivity density J:180651
decreased trabecular bone thickness J:180651
decreased trabecular bone volume J:180651
postnatal growth retardation J:180651
normal skeleton phenotype J:180651
Casrtm1Wch/Casrtm1Wch
Tg(Vil1-cre)997Gum/0
involves: 129S4/SvJae * C57BL/6J * SJL
abnormal enterocyte proliferation J:179672
abnormal large intestine crypts of Lieberkuhn morphology J:179672

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/09/2018
MGI 6.12
The Jackson Laboratory