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Tg(PTH-cre)4167Slib
Transgene Detail
Summary
Symbol: Tg(PTH-cre)4167Slib
Name: transgene insertion 4167, Steven K Libutti
MGI ID: MGI:2683304
Synonyms: PTH-cre, Tg(PTH-cre)1Slib
Transgene: Tg(PTH-cre)4167Slib  Location: unknown  
Alliance: Tg(PTH-cre)4167Slib page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(PTH-cre)4167Slib expression driven by 1 gene
 
Mutation detailsA 5' upstream regulatory region of the human PTH gene was adjoined to sequence encoding cre recombinase followed by a metallothionein 1 polyadenylation signal. The expression of cre recombinase is parathyroid cell specific. (J:86642)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: PTH (human)
Summary of all recombinase alleles driven by PTH.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(PTH-cre)4167Slib
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:86642 Libutti SK, et al., Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism. Cancer Res. 2003 Nov 15;63(22):8022-8
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory