Taf7 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Taf7
TATA-box binding protein associated factor 7
MGI:1346348

13 phenotypes from 2 alleles in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Taf7^tm1.1Dss/Taf7^tm1.1Dss involves: C57BL/6	abnormal embryo development	J:185745
Taf7^tm1.1Dss/Taf7^tm1.1Dss involves: C57BL/6	embryonic lethality, complete penetrance	J:185745
Taf7^tm1.1Dss/Taf7^tm1.2Dss Tg(Cd8a*-cre)B8Asin/0 involves: C57BL/6	abnormal T cell differentiation	J:185745
	decreased CD4-positive, alpha-beta T cell number	J:185745
	decreased CD8-positive, alpha-beta T cell number	J:185745
	decreased double-positive T cell number	J:185745
	decreased single-positive T cell number	J:185745
	decreased T cell number	J:185745
	decreased T cell proliferation	J:185745
	decreased thymocyte number	J:185745
Taf7^tm1.1Dss/Taf7^tm1.2Dss Tg(Lck-cre)1Cwi/0 involves: C57BL/6	abnormal T cell differentiation	J:185745
	abnormal thymus physiology	J:185745
	decreased CD4-positive, alpha-beta T cell number	J:185745
	decreased CD8-positive, alpha-beta T cell number	J:185745
	decreased double-positive T cell number	J:185745
	decreased thymocyte number	J:185745
	increased double-negative T cell number	J:185745
	small thymus	J:185745

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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