Adamts5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adamts5
ADAM metallopeptidase with thrombospondin type 1 motif 5
MGI:1346321

9 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adamts5^tm1.1Eam/Adamts5⁺ involves: 129S5/SvEvBrd	decreased susceptibility to induced arthritis	J:97590
Adamts5^tm1.1Eam/Adamts5^tm1.1Eam involves: 129S5/SvEvBrd	decreased susceptibility to induced arthritis	J:97590
Adamts5^tm1.1Lex/Adamts5^tm1.1Lex involves: 129S/SvEvBrd	normal skeleton phenotype	J:120892
Adamts5^tm1Dgen/Adamts5^tm1Dgen B6.129P2-Adamts5^tm1Dgen/J	interdigital webbing	J:155754
Adamts5^tm1Dgen/Adamts5^tm1Dgen B6.129P2-Adamts5^tm1Dgen/J	syndactyly	J:155754
Adamts5^tm1Eam/Adamts5⁺ involves: 129S5/SvEvBrd	no abnormal phenotype detected	J:97590
Adamts5^tm1Lex/Adamts5^tm1.1Lex Tg(CMV-cre)1Cgn/? involves: 129S5/SvEvBrd * BALB/cJ	abnormal cartilage morphology	J:105138
	normal reproductive system phenotype	J:105138
Adamts5^tm1Lex/Adamts5^tm1Lex Tg(CMV-cre)1Cgn/0 involves: 129S5/SvEvBrd * BALB/cJ	osteoarthritis	J:105138
Adamts5^tm2.2Lex/Adamts5^tm2.2Lex B6.129S5-Adamts5^tm2.2Lex	abnormal pain threshold	J:175366
Adamts5^tm2.2Lex/Adamts5^tm2.2Lex B6.129S5-Adamts5^tm2.2Lex	decreased susceptibility to induced arthritis	J:175366

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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