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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
MGI:1346321
9 phenotypes from 6 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Adamts5tm1.1Eam/Adamts5+
involves: 129S5/SvEvBrd
decreased susceptibility to induced arthritis J:97590
Adamts5tm1.1Eam/Adamts5tm1.1Eam
involves: 129S5/SvEvBrd
decreased susceptibility to induced arthritis J:97590
Adamts5tm1.1Lex/Adamts5tm1.1Lex
involves: 129S/SvEvBrd
normal skeleton phenotype J:120892
Adamts5tm1Dgen/Adamts5tm1Dgen
B6.129P2-Adamts5tm1Dgen/J
interdigital webbing J:155754
syndactyly J:155754
Adamts5tm1Eam/Adamts5+
involves: 129S5/SvEvBrd
no abnormal phenotype detected J:97590
Adamts5tm1Lex/Adamts5tm1.1Lex
Tg(CMV-cre)1Cgn/?
involves: 129S5/SvEvBrd * BALB/cJ
abnormal cartilage morphology J:105138
normal reproductive system phenotype J:105138
Adamts5tm1Lex/Adamts5tm1Lex
Tg(CMV-cre)1Cgn/0
involves: 129S5/SvEvBrd * BALB/cJ
osteoarthritis J:105138
Adamts5tm2.2Lex/Adamts5tm2.2Lex
B6.129S5-Adamts5tm2.2Lex
abnormal pain threshold J:175366
decreased susceptibility to induced arthritis J:175366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory